| Overall tolerability was similar between the two classes of drugs, but atypical agents caused fewer extrapyramidal side effects. |
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| The efficacy and tolerability of a butterbur root extract for the treatment of asthma was analyzed in a prospective, nonrandomized, open trial. |
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| Safety and tolerability were good, with no drug-related adverse events or changes in clinical or laboratory parameters. |
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| Safety and tolerability of oral loading divalproex sodium in acutely manic bipolar patients. |
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| These results confirm the safety, tolerability and the preliminary efficacy of PCK3145 at all dose levels tested. |
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| This new indication is testament to its efficacy and good tolerability profile. |
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| Other outcome measures are safety and tolerability of the drug as well as any changes in progression of disability. |
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| The primary objectives of the trial are to determine the safety and tolerability of ThGLP-1 in both healthy subjects and diabetic patients. |
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| Analysis regarding the results of clinical trials may not provide definitive results regarding safety, tolerability or therapeutic benefits. |
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| Thereafter, the dose of INHIBACE must be adjusted according to individual tolerability, response, and clinical status. |
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| Patients will continue to be monitored to track disease status, survival and long-term tolerability. |
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| This combined action is likely responsible for its unique antidepressant tolerability profile. |
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| The AD02 vaccine, developed with British drugmaker GlaxoSmithKline, was already tested for safety and tolerability over the past year. |
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| These trials demonstrated that when administered alone, ezetimibe has an excellent tolerability profile similar to placebo. |
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| In this phase, researchers determine the tolerability of the drug and monitor carefully for any harmful side effects. |
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| The tolerability of the different concentrations was assessed after weekly instillations into the urinary bladder for 6 weeks. |
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| Angiotensin receptor antagonists are similar to ACE inhibitors in utility and tolerability, but instead of blocking the production of angiotensin II, they completely inhibit its binding to the angiotensin II receptor. |
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| Though he supposed he had Legoland to blame: its tolerability had led him too easily into agreeing to SeaWorld, which even on Celexa, he now saw, would have been another prospect entirely. |
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| The responsiveness and tolerability to methotrexate is not the same as it is in R. A., though it can work very well in some and is worth considering. |
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| Promising efficacy and tolerability data have been reported from a phase II study in patients with advanced NSCLC, when BIBF 1120 was administered as monotherapy. |
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| While some recent studies have shown that chemotherapy may extend the life span of some patients, the survival advantage and tolerability are still very low. |
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| Weight reduction is significant and the tolerability profile is very good. |
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| Subject to a tolerability test, microbiologically tested. |
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| Important considerations include crossclade reactivity, tolerability, and durability of response. |
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| Dose dependent tumor regression and good tolerability in a mouse mastocytoma model. |
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| The data show that ADX71149 met the primary objectives of safety and tolerability. |
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| Phase I trials were performed to establish immunogenicity and tolerability of a range of doses of monovalent HPV L1 vaccines. |
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| The study will evaluate the safety and tolerability of a new, oral tablet formulation. |
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| Although these predefined tolerability assessments are characteristic of the known safety profile of sunitinib, they are not exhaustive, and as such, may not sufficiently describe the tolerability profile of the compound. |
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| Positive long-term safety and tolerability data are now available. |
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| Drossman does not favor TCAs such as amitriptyline, which may cause side effects that limit tolerability through anticholinergic and antihistaminergic effects. |
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| As such, pegylated interferon may offer advantages over standard interferon because it could provide longer exposure to the drug, while still maintaining tolerability. |
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| Neuren's Phase 2a clinical trial investigated the safety, tolerability and pharmacokinetics of a 4-hour infusion of Glypromate in 33 cardiac surgery patients. |
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| Controlled, double-blind, multicentre clinical trial to investigate long-term tolerability and efficacy of trospium chloride in patients with detrusor instability. |
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