How to use receptor in a sentence

Looking for sentences and phrases with the word receptor? Here are some examples.

Sentence Examples In the climacteric fruit tomato, ethylene is perceived by a family of six receptor proteins. Macrophages, scavenger-like cells that roam the body, have a surface receptor called CD 163 which binds the protein haptoglobin. This mechanism might contribute to the increased response of the insulin receptor as observed when subjected to acylated insulin. At this average receptor density, if all the particles are homogeneous, there are too few receptors on any particle to support any adhesion. Their growth hormone and testosterone levels are higher, and they have more testosterone receptor sites. Neither is equivalent to protein activation, which is the functionally activated form of the receptor. The growth hormone binds to its receptor on target cells, then creates some particular action. Abstract Olfactory receptor neurons respond to odorants with characteristic patterns of action potentials that are relevant for odor coding. So, in this process they become conditioned to the kinesthetic and proprioceptive receptor inputs. Interaction with the receptor of the target cell may be essential for this conformational change and the conformation itself. When the receptor bound to CD19 on leukemic cells, it set off a reaction that super-charged the killing activity of the NK cell. Stimulation of a beta receptor causes muscle vasodilation, bronchial relaxation, and cardiac acceleration. Normal cells harbor this receptor, too, but it's usually occupied by the protein laminin. The diagnosis is confirmed by the tensilon test, electromyographic studies and the finding of elevated acetylcholine receptor antibodies. So the problem was how to change this catechol without affecting the drug's ability to interact at the receptor. Other treatments recommended for bone loss are specific oestrogen receptor modulators, intranasal calcitonin, and bisphosphonates. The LDL receptor is a polypeptide of 839 amino acids that spans the plasma membrane. For example, thyroxine for thyroid cancer, tamoxifen for oestrogen receptor positive breast cancer, and stilboestrol for cancer of the prostate. Specifically, nicotine acts at the nicotinic receptor class for the transmitter acetylcholine. When the neurotransmitter binds to its receptor, it activates the second messenger system. Show More Sentences The serotonin type 3 receptor is a member of a superfamily of ligand gated ion channels. Thus, the researchers proposed the hypothesis that alcohol releases endogenous opioids and that naltrexone blocks the opioid receptor. Muscle receptor afferents are involved in the level and timing of respiratory activity. Rather, all known abused drugs affect a limited number of neurotransmitters by agonism or antagonism of a specific receptor site. These observations provide support for the model that glucose and structurally related sugars are agonists of the Gpr1 receptor. Opioid receptor agonists act at sites that are distributed throughout this circuit to produce analgesia. This receptor kinase can recognize a structure on bacterial pathogens called flagellin that makes the bacteria motile. By binding intramolecularly to the receptor, the tethered ligand causes transmembrane signaling. Then the scientists mated mice deficient in the GIP receptor with mice that lack leptin, a hormone that signals satiety. The affinity between the mutually complemental antibody and receptor was described by a weighted affinity matrix. In addition to binding to GHR, human GH binds to the prolactin receptor and is unique in its lactogenic activity. The discovery of a specific taste receptor on the human tongue for glutamates in 2000 legitimized its existence as a basic flavor. The use of the opiate antagonist, naltrexone in the treatment of autism is reasonable since it antagonizes endogenous opiate receptor activity. Other factors, including drug potency, receptor affinity, and pharmacokinetics also influence these outcomes. The receptor soaks up angiogenic growth factors, depriving blood vessels in the brain, lungs, and kidneys of essential maintenance tools. The rate of estrogen receptor positivity is significantly higher among men than women with breast cancer. It diffuses across the synaptic cleft and binds to the end organ adrenergic receptor. Researchers from the University of Miami have isolated a receptor that binds glutamate and have proposed that it underlies the umami taste. Interestingly, blockade of this receptor not only seems to affect appetite, but also seems to help with cravings for nicotine. Computer-aided instruction augments learning in all topics, but most commonly in the areas of receptor theory and mechanism and stereochemistry. Show More Sentences Thus, in some parts of the retina the larval rhabdoms are incorporated into the receptor array. Within cells both retinol and retinoic acid bind to specific receptor proteins. Mice and dogs, which have intense senses of smell, have mostly intact olfactory receptor genes. Ephrin B2 is the entry receptor for Nipah virus, an emergent deadly paramyxovirus. Some steroid hormones, such as glucocorticoids, bind to a cytoplasmic receptor protein that is then translocated into the nucleus. Induction of matrix receptor and inhibin may facilitate the inflammatory reaction in sepsis. Medicines called ACE inhibitors and angiotensin-II receptor blockers are helpful. It seems probable that the initial event in the toxicity of PCBs is mediated through their binding to the aryl hydrocarbon receptor. As pharmacologists, we want to understand how patterns of activity at receptor populations associate with mental phenomena. The myochordotonal organ is a muscle receptor organ situated at the proximal end of the meropodite in the walking legs of crabs. Herein, we would like to add activating a topic receptor as a proapoptotic stimulus for its cells in the Table. Pain perception begins at the receptor site that responds to damaging stimuli. Urokinase bound to its receptor maintained fibrinolytic activity over 24 hours in the rabbits. In addition, these ligands markedly upregulated production of CD36, a scavenger receptor that regulates phagocytosis of apoptotic neutrophils. Stimulation of this receptor initiates the cascade of events that eventually results in the repair of muscle and growth of new muscle. Once it finds and binds to a target receptor, a ripple-like cascade of events is initiated inside that cell. That approach is limited to proceeding no further than the stimulation of sensory receptor sheets. In crustacean larval eyes, the receptor array is tightly bunched into a sphere surrounding the geometrical center of the eye. The dark-adapted S. coeruleus cell, when subjected to a step-like increase in light intensity, responds with a depolarizing receptor potential. Little is known about the involvement of receptor genes in the ethylene perception of monocotyledonous plants such as rice. Show More Sentences A variety of treatments, from vitamins to alpha and beta adrenergic receptor blockers, have been suggested for tetanus. The particular parts of a drug that cause it to bind to its receptor are together termed the pharmacophore. Chronic stimulation of the receptor causes an increase in the synthesis of a major thyroid hormone precursor, thyroglobulin. Drugs perturb the system through increasing or decreasing transmission or transmitter levels, or up or down regulating receptor populations. A missing receptor molecule contributes to the growth of tumors in human ovaries. Each sense organ has specialized receptor cells to detect the appropriate type of physical energy or stimulation. By adding and subtracting methyl groups, the two enzymes can adjust receptor sensitivity to mitigate the effect of ligand binding. This drug has minimal activity at histaminic, serotonergic, cholinergic or adrenergic receptor sites. In addition, muscarinic receptor stimulation augmented the mitogenic responses of human airway smooth muscle cells to epidermal growth factor. Could these gene products represent upstream components in a common signal transduction pathway such as a receptor or signal transducers? The transferrin receptor is a protein located in the plasma membrane that binds the protein transferrin. The gene makes a receptor protein that is stimulated by a brain hormone called vasopressin. It is generally difficult to discern the complete repertoire of other chemosensory receptor genes in mammals. It binds to a number of receptor sites in the body, including serotonin, adrenergic and dopaminergic receptors. The NMDA receptor is activated by glutamate, the primary excitatory neurotransmitter in the brain. Different levels of the receptor are thought to explain the very different behaviours of meadow voles and prairie voles. Taste is detected by the chemosensory organs that are found in an animal's gustatory or tactile receptor systems. Further studies may provide insight into the precise role of this receptor in neuroendocrine cells. This indicates that the helix is probably fluxional even when the receptor is not activated. The concentration of androgen receptor and 5 reductase activities in frontal hair follicles is greater than in occipital follicles. Show More Sentences Receptor stimulation produced no change in receptor density, which suggests that the receptors are prearranged into signalling islands. Several forms of familial hypercholesterolemia are the result of genetic defects in the gene encoding the receptor for low-density lipoprotein. All are viewed dispassionately, the heart as a pump, the brain as a network of neural tissues, the eye as a receptor of visual stimuli. Finally, the presence of a specific receptor in the target tissue is required for a hormone to have its effect. When the neurotransmitter binds with the receptor, the next cell responds accordingly. The neurotransmitter and receptor are specific to each other, like a lock and key. Hormones work by docking with a specific receptor on a cell, which then responds by turning on genes. The blue light receptor has been considered to be the only light receptor that induces a phototropic response. The apical processes of receptor cells in the macula project into a gelatinous mass, the otolithic membrane. Histamine H 2 receptor antagonists act by blocking the effect of histamine on parietal cells. Conductive hearing loss does not involve damage to the receptor cells or any other nerve cells in the auditory pathway. This protein is embedded in and extends exterior to the viral lipid membrane and is primarily responsible for host cell receptor binding and host cell tropism. The binding of a chemical cue to an odorant receptor activates G proteins initiating a signal transduction cascade that results in a behavioral response. Pharmacologically, it is characterized by the constitutive activity of the ligand-free receptor, and by the inverse, partial, and full agonism due to the bound ligand. Glutamate is released presynaptically and binds to a postsynaptic receptor gating a cation-selective channel, thus depolarizing the post-synaptic cell. The Miraculin binds to the sweet receptor in your mouth and makes sour, or acidic foods taste incredibly sweet. The receptor recognition site can change its electrovalence and exchange divalent or monovalent counter ions for either decamethonium or muscarone. Both pufferfish and zebrafish have a second glucagon receptor-like gene that is most closely related to the characterized goldfish glucagon receptor. About nine per cent of people have at least one copy of a gene for 5HT2a that call for the amino acid tyramine at one point in the receptor protein. The perception of spatial movement and orientation of the body as a whole also involves a fluid filled receptor system located in the vestibules of the inner ear. Show More Sentences An agonist drug molecule has good affinity with the receptor, and when it combines with the receptor, the drug molecule produces a cellular effect. Studies have clearly demonstrated that key therapies in the acute attack of migraine share the common pharmacologic activity of serotonin receptor agonism. An improved understanding of the receptor subtypes involved in state-dependent control of upper airway motoneurons may help establish more effective treatments. Usually, anacolutha are close enough to a grammatical construction, or can be traced back to a familiar pattern, to be understood without problem by the receptor. They may mimic naturally occurring steroids, act as hormone receptor agonists or antagonists or alter the enzymes responsible for hormone synthesis and degradation. Over the past three decades a great deal of evidence has accumulated in favor of the hypothesis that steroid receptor hormones act via regulation of gene expression. Extracts of diesel exhaust particles modulate the aryl hydrocarbon receptor and estrogen-dependent gene expression in cells in vitro and are endocrine disrupters. The nicotinic acetylcholine receptor is a ligand-gated ion channel found in the neuromuscular junction of vertebrates and the electrocytes of electric fish. Also, it is the surface receptor of the virus, bacteriophage lambda. I think the above article misspells the receptor abbreviation. Altered estrogen receptor sensitivity is another possible abnormality, but like the estrogen-androgen imbalance suggestion, it is completely conjectural. If agouti binds to this receptor, melanocytes make the red-yellow pigment. Obese people are also believed to have a faulty receptor in their brains, which is meant to measure levels of leptin, a protein produced by fatty tissue. But unlike alcohol, Xanax only affects one specific type of brain receptor. For example, problems include a low transduction of tumour cells because of their low expression of the Coxsackie adenovirus receptor required for adenoviral entry. In isolated cilia and in intact olfactory receptor neurons, studies have shown basal activities of both adenylate cyclase and cAMP phosphodiesterase. The response of cells to the binding of glucagon to its cell surface receptor is the activation of the enzyme adenylate cyclase which is associated with the receptor. Any patient with a history of angioneurotic edema, whether related to an ACE inhibitor, angiotensin receptor blockers, or another cause, should not be given an ACE inhibitor. When the antagonist drug molecule is occupying the receptor site, it blocks the agonist molecules from combining with the receptor site and hence blocks a cellular response to the agonist drug. Following IVIG therapy in patients with ITP, platelet counts generally rise, apparently by Fc receptor blockade of splenic phagocytes and other reticuloendothelial cells. Show More Sentences How likely is it that these mutations in the nicotinic receptor genes completely eliminate the functional activity of the encoded receptor protein? Particular versions of dopamine receptor genes have been associated with higher physical activity and lower body mass index. Once in the system, it binds with opioid receptor cells that send endorphins shooting through the body. Some nonclassical MHC molecules function as a ligand to a natural killer cell receptor and send a signal to prevent the cell lysis by the NK cell. Muscle spindles and Golgi tendon organs are receptor organs found inside skeletal muscle, which are stimulated by stretch of the muscle or tension on the tendon. The receptor organ of posture and equilibrium is a composite one located in the semicircular canals, the utricle, and the saccule of the inner ear. Reversal of aging-associated hippocampal synaptic plasticity deficits by reductants via regulation of thiol redox and NMDA receptor function. The lysophosphatidic acid 2 receptor mediates down-regulation of Siva-1 to promote cell survival. We're aiming to develop molecules that target the glycine receptor into a drug that can be administered as a tablet. Certain peptides secreted by the bacteria themselves bind to a receptor called AgrC and trigger the bacteria to make toxins. NgR1 is a receptor for three proteins found in myelin, the insulating substance that ensheathes axons. Noncompetitive functional inhibition at diverse, human nicotinic acetylcholine receptor subtypes by bupropion, phencyclidine, and ibogaine. Angiotensin II receptor blockers in patients with ACE inhibitor-induced angioedema. Fetopathy associated with exposure to angiotensin converting enzyme inhibitors and angiotensin receptor antagonists. Alteration of reproductive function but not prenatal sexual development after insertional disruption of the mouse estrogen receptor gene. We know that the Z-drugs, some of the most widely used pharmacologies for insomnia, are benzodiazepine receptor agonists. Rapid solution exchanges were accomplished through a series of flow pipes mounted onto a piezoelectric bimorph to evoke NMDA receptor currents. Indeed, for its colliculoretinal transport, BDNF needs to bind to its receptor in order to be internalized into a transport vesicle. The bioflavonoid galangin blocks aryl hydrocarbon receptor activation and polycyclic aromatic hydrocarbon-induced pre-B cell apoptosis. Both the smallpox vaccine and HIV exploit a receptor called CCR5, which is expressed on the surface of white blood cells. Show More Sentences Mutations in the colony stimulating factor 1 receptor have recently been identified to be the cause of this microgliopathy. Pigs are one of four known mammalian species which possess mutations in the nicotinic acetylcholine receptor that protect against snake venom. It constituted back then the second receptor of French immigrants in the New World after the United States. A study discovered that a mutation in genes encoding both Neurokinin B as well as the Neurokinin B receptor can alter the timing of puberty. Morphine binds to and activates mu opioid receptor in the brain, spinal cord, stomach and intestine. A combination of an androgen and a progestin seems promising, as do selective androgen receptor modulators. Angiotensin converting enzyme inhibitors and angiotensin II receptor antagonists for preventing the progression of diabetic kidney disease. Heterodimerization of the Drosophila ecdysone receptor with retinoid X receptor and ultraspir acle. The xenoestrogen bisphenol A induces inappropriate androgen receptor activation and mitogenesis in prostatic adenocarcinoma cells. Adenosine is a naturally occurring signal molecule that acts at multiple adenosine receptor subtypes to modulate key cardio-renal functions. However, affinity towards the gamma-amino butyric acid receptor has also been demonstrated. Uptake of nonopsonized bacteria by macrophages seems to be mediated dominantly by the mannose receptor. Intriguingly, the rat C1b isoform of the calcitonin receptor has very little interaction with the thyroidally derived form of calcitonin. In contrast, intact sweet receptor genes were found in aardwolf, Canadian otter, spectacled bear, raccoon, and red wolf. Eszopiclone is believed to interact with the GABA-receptor complex at binding domains close to the benzodiazepine receptor. Testosterone increases human platelet thromboxane A2 receptor density and aggregation responses. Of the wine set, 29 out of the 36 compounds elicited clear excitatory responses in at least one receptor neuron. Autoantibodies that act like hormone agonists can produce states of hyperfunction or hypofunction when acting as receptor antagonists. At the extremes, there can be both nociceptor activation without pain or pain without receptor activation. Of the leukotriene receptor antagonists, the most data are available on montelukast. Show More Sentences The candidates are both immunotoxins comprising an antibody fragment that targets the CD22 receptor on B-lymphocytes fused to a toxin molecule. A limitation of this study is that ligand binding does not necessarily indicate agonism of the receptor, leading to transcriptional events. Angiotensin receptor blockers have a mild uricosuric effect and may help with lowering uric acid levels. Each channel opens its gates only after a molecule called adenosine triphosphate binds to a receptor on the channel. MicroRNA-155 regulates angiotensin II type 1 receptor expression and phenotypic differentiation in vascular adventitial fibroblasts. Many RNA interference and insertional mutation lines were used to knockdown or reduce the expression level of a defined 5-HT receptor. The resulting shards of fibrinogen then bind to and activate TLR4, a receptor protein found on immune cells and other cells lining the airways. With the side chain anchored in the exosite, the active saligenin head binds to and activates the b receptor at the same location as albuterol. Its mode of action is different from alkalinizing agents such as antacids or histamine-2 receptor blockers and also proton pump inhibitors. Its mode of action is antagonising the effect of aldosterone at levels of the mineralocorticoid receptor. Evidence for a specific mineralocorticoid receptor in rat pituitary and brain. Falsepositive somatostatin receptor scintigraphy due to an accessory spleen. Both Merck's MK-0893 and Eli Lilly's LY2409021 suppress glucagon action via receptor blockade. Other glaucoma medications available include alpha-adrenergic receptor agonists and carbonic anhydrase inhibitors. Inhibition of erbB receptor tyrosine kinases as a strategy to abrogate antioestrogen resistance in human breast cancer. Inhibition of dopamine release via 5HT2A receptor agonism has been supported by radioreceptor labeling and positron emission tomography scans. The best recognized role of apo E in lipid metabolism is as a ligand for receptor mediated clearance of chylomicron and VLDL remnants. The a-ring lactone of brevetoxin PbTx-3 is required for sodium channel orphan receptor binding and activity. The HIRMAb part of the HIRMAb-EPO fusion protein cross-reacts with the Rhesus monkey insulin receptor. Gonzalez of the National Cancer Institute and his colleagues bred a strain of mice lacking the gene for the aryl hydrocarbon receptor. Show More Sentences Many man-made pollutants activate the aryl hydrocarbon receptor and are risk factors for type 2 diabetes. Another specialized type of T cell, the Natural Killer T cell, was found to have high expression of the receptor. Kisspeptin, a peptide that activates the kisspeptin receptor, is encoded by the KISS1 gene. It is advertised to be a N-methyl-D-aspartate receptor activator and testosterone releaser. A family with hypogonadotropic hypogonadism and mutations in the gonadotropin releasing hormone receptor. Kynurenic acid is the only known endogenous N-methyl-D-aspartate receptor antagonist found in humans. Nuclear receptor sites for vitamin Dsoltriol in midbrain and hindbrain of Siberian hamster assessed by autoradiography. Functionally significant insulin-like growth factor 1 receptor mutations in centarians. The serotonin 2C receptor potently modulates the head-twitch response in mice induced by a phenethylamine hallucinogen. Expression of oestrogen receptor alpha and beta mRNAs in prostate cancer treated with leuprorelin acetate. Ontogeny of androgen receptor immunoreactivity in lumbar motoneurons and in the sexually dimorphic levator ani muscle of male rats. The ER membrane contains a srca plasmic reticulum calcium ATPase pump, a calcium leak and an IP3 receptor channel. The drug blocks the binding of IgE to the IgE receptor on the surface of mast cells and basophils. Unlike other treatments for HAE, FIRAZYR is the first bradykinin receptor antagonist, offering a unique mechanism of action. The NR2B gene is part of a brain cell receptor that acts like an antenna, receiving chemical signals from other neurons. Each peg sensillum has a single slitlike pore that allows chemical stimulants access to receptor neurons inside the peg shaft. The patterns of positive selection across mammalian, avian and aquatic vertebrate genomes show that sensory receptor genes are highly conserved. This sensory receptor, located in the roof of the mouth, receives and analyses chemical traces picked up in the air by the snake's forked tongue. The peptide part directs the conjugates specifically to LHRH receptor expressing tumor cells, and mediates binding and uptake via endocytosis. Autocrine-paracrine VEGF loops potentiate the maturation of megakaryocytic precursors through Flt 1 receptor. Show More Sentences Serotonin may mediate erectogenic effect through several different types of serotonin receptor proteins in the brain. These distinct groups of genes, along with Fc receptor genes, were the major genes altered by TCDD and DEX in the DC maturation pathway. Downregulation of kappa opioid receptor mRNA levels by chronic ethanol and repetitive cocaine in rat ventral tegmentum and nucleus accumbens. Cellular uptake of folates may be mediated by a reduced folate carrier, a proton-coupled folate transporter, or a high-affinity folate receptor. Mitogenic properties of insulin and insulin analogues mediated by the insulin receptor. When progesterone binds to the receptor, it sends a signal that's transferred to the cell nucleus. Gabapentin receptor alpha2delta-1 is a neuronal thrombospondin receptor responsible for excitatory CNS syn aptogenesis. Activation of the nuclear receptor FXR enhances hepatocyte chemoprotection and liver tumor chemoresistance against genotoxic compounds. Fingolimod is in a class of medications called sphingosine l-phosphate receptor modulators. Toll-like receptor 2 functions as a pattern recognition receptor for diverse bacterial products. Spontaneous glutamate release is independent of calcium influx and tonically activated by the calcium-sensing receptor. Ionotropic purinergic receptor P2X4 is involved in the regulation of chondrogenesis in chicken micromass cell cultures. This receptor is found on a number of tumor types, including T cell and Natural Killer cell lymphomas, as well as multiple myeloma. Perfluorooctane sulfonate affects hormone receptor activity, steroidogenesis, and expression of endocrine-related genes in vitro and in vivo. Estradiol and bisphenol A stimulate androgen receptor and estrogen receptor gene expression in fetal mouse prostate mesenchyme cells. These lipids fasten onto a molecule called a receptor on the surface of microglial cells. All vit D metabolites bind the VDRs, but most of the biological effects are likely mediated by calcitriol due to its greater receptor affinity. The team found that the redeye gene encodes a subunit of the nicotinic acetylcholine receptor. EnVivo's lead product, EVP-6124, is an alpha-7 nicotinic acetylcholine receptor agonist. Varenicline is a selective nicotinic acetylcholine receptor partial agonist developed for explicit use in smoking cessation. Show More Sentences Impaired nociception and pain sensation in mice lacking the capsaicin receptor. The subnuclear three-dimensional image analysis of androgen receptor fused to green fluorescence protein. Tie2 is a receptor tyrosine kinase expressed on vascular endothelial cells, which plays a key role in stabilizing blood vessels. Norgestrel and gestodene stimulate breast cancer cell growth through an oestrogen receptor mediated mechanism. The team knocked out the gene for a protein called nuclear receptor corepressor 1 in the muscles of mice. The technique uses a zinc finger nuclease, a protein that can break up pieces of DNA, to effectively inactivate the receptor gene. Belsomra is an orexin receptor antagonist and is the first approved drug of this type. Signaling through the RANK receptor contributes to osteolysis and tumor growth. A truncated form of leptin receptor, Ob-Ra, was predominant in placenta and vascular tissues. Second, the receptor deactivates insulin-like growth factor-II, which normally stimulates cell growth. Both gastrin and the CCK-B receptor are overexpressed in pancreatic cancer. The insectotoxins may also target the insect post-synaptic glutamate receptor. Erlotinib, gefitinib and afatinib inhibit tyrosine kinase at the epidermal growth factor receptor. Guanfacine is a selective alpha-2A adrenergic receptor agonist in that it has 15-20 times higher affinity for this receptor subtype than for the alpha-2B or alpha-2C subtypes. Upon ligand binding, receptor homodimerization or heterodimerization occurs, which is followed by autophosphorylation and activation of the tyrosine kinase domains. Numerous compounds which inhibit renin, ACE, and the angiotensin II receptor have been used in the treatment of high blood pressure for the last 30 years. This compound had fewer adverse effects than caffeine since it only blocks only the A2A adenosine receptor subtype, and at the same time it is significantly more effective. Both analgesia and drug addiction are functions of the mu opioid receptor, the class of opioid receptor first identified as responsive to morphine. We also propose that hyposialylation would dampen the phosphorylation level of the MET receptor and, therefore, result in the disengagement of its downstream pathways. Moreover, her team reports test tube studies showing that a drug that blocks this receptor slows the growth of medulloblastoma and glioblastoma cells. Show More Sentences Human chorionic gonadotropin induces neuronal differentiation of PC12 cells through activation of stably expressed lutropin choriogonadotropin receptor. For instance, when Abbott and his colleagues attached a receptor called biotin to the lipids, the sensor detected a bacterial protein that binds to biotin. This protein is a receptor for leptin and is involved in the regulation of fat metabolism and of a novel hematopoietic pathway required for normal lymphopoiesis. Isolated lymphoid follicle formation is inducible and dependent upon lymphotoxin-sufficient B lymphocytes, lymphotoxin beta receptor, and TNF receptor I function. Calando's first therapeutic contains a targeting ligand the cell surface receptor for which is over-expressed on a wide variety of different cancers. Mammals need two genes to make the taste receptor for sugar. Studies in various cats showed that one of these genes has mutated and no longer works. Exforge utilizes two complementary mechanisms of action through the calcium channel blocker amlodipine and the angiotensin receptor blocker valsartan. Ulipristal acetate was developed as a selective progesterone receptor modulator with pure progesterone receptor antagonistic activity and minimal antiglucocorticoid effects. The structures and functions of the sensilla of EGW adults still need to be further investigated by immuno-electron microscopy and by single-cell receptor potentiometry. Varenicline is a partial agonist of the nicotinic acetylcholine receptor. Cytisine is a natural plant compound that works like the quit-smoking drug varenicline, marketed as Chantix, by attaching to a protein receptor molecule on neurons. These findings indicate that increased expression of metabotropic glutamate receptor 1 promotes the occurrence of high-fat diet-induced preeclampsia in pregnant rats. Substances known to specifically block the platelet's P2Y 12 receptor include the thienopyridine class of drugs, including clopidogrel, prasugrel, ticagrelor, and ticlopidine. It is a selective neuronal nicotinic receptor antagonist and the S-isomer of mecamylamine, a drug previously marketed for use in resistant hypertension. The two proteins added today are phosphodiesterase IV and peroxisome proliferator-activated receptor delta, both are active targets of structure based drug design. Formation of the 67-kDa laminin receptor by acylation of the precursor. Insulin-like growth factor-I receptor overexpression mediates cellular radioresistance and local breast cancer recurrence after lumpectomy and radiation. In the current study, morphine tolerance was investigated using baclofen drug as an agonist and CGP35348 as a selected antagonist of GABA-B receptor. This receptor activation can inhibit the sodium potassium chloride cotransporter and produce a loop-diuretic effect with natriuresis and kaliuresis. A significant association was identified between alterations in the RAR-related orphan receptor beta gene, one of the circadian clock genes, and having bipolar disorder. Show More Sentences The researchers could tell when an orphan receptor had hooked a molecule by monitoring signaling events, such as waves of calcium ions, in the cells. Within the NMDA receptor are various subunits, and Magnusson said that research keeps pointing back to the GluN2B subunit as one of the most important. Under the terms of the agreement, DanioLabs will use their proprietary IBD model to screen compounds from Oxagen's G-protein coupled receptor program. The researchers had been working with a specific glycan that binds to a key B-cell receptor, called CD22, involved in suppressing B-cell activation and apoptosis. Gilenya is the first oral therapy approved to treat relapsing forms of MS and the first in a new class of compounds called sphingosine 1-phosphate receptor modulators. Selective oestrogen receptor modulators for uterine leiomyomas. The effects of dexamethasone, ascorbic acid, and p-glycerophosphate, on osteoblastic differentiation by regulating estrogen receptor and osteopontin expression. In addition, ATI receptor signaling contributes to constriction of renal and systematic arterioles, increased cardiac contractility, and sodium uptake in the kidney. Exenatide is a glucagon-like peptide-1 receptor agonist that is commonly used in the treatment of type II diabetes mellitus for its effects on the incretin system. The glucocorticoid receptor gene NR3C1 has been widely studied in other inflammatory and autoimmune diseases, such as cystic fibrosis, asthma, and Graves ophthalmopathy. Gilenya is a sphingosine 1-phosphate receptor modulator, which reduces the frequency of clinical exacerbations and delays the accumulation of physical disability. They then tested the impact this variant had on retinal pigment epithelial cells in humans and in mice, including wild-type and toll-like receptor 3 knockout animals. Rapid and reliable genotyping for the Toll-like receptor 4 A896G polymorphism using fluorescence-labeled hybridization probes in a real-time polymerase chain reaction assay. These 5 subtypes are luminal A and luminal B, normal breastlike, human epithelial growth factor receptor 2 overexpressing, and basal-like subtypes. The receptor also contributes to phagocytosis of opsonized microorganisms. Movantik belongs to a class of drugs called peripherally acting opioid receptor antagonists, which are used to decrease the constipating effects of opioids. Schornack s lab that a mutant of SymRK receptor which is unable to develop mycorrhization show extensive colonization by the root pathogenic oomycete Phytophthora palmivora. These include purinergic receptor antagonism, TRP channel antagonism, cannabinoid receptor agonism, melatonin modulation and apoptosis-inducing agents. Previous studies have shown that FES uptake corresponds to levels of estrogen receptor expression, which in turn has been linked to response to therapy by in vitro studies. Central benzodiazepine receptor agonists have been known to induce multiple effects including anxiolytic, myorelaxant, anticovulsant, hypnotic and amnestic effects. Show More Sentences Degarelix, a gonadotropin releasing hormone receptor antagonist, helps suppress the testosterone secretion so that it can inhibit the growth of prostate cancer. The proper form and dose of zinc blocks the ICAM-1 receptor, thus preventing the rhinovirus from entering cells and establishing a common cold infection. Autoradiographic and immunohistochemical localization of insulin-like growth factor-I receptor binding sites in brain of the brown trout, Salmo trutta. Naloxone, an opioid receptor antagonist, quickly and powerfully reverses the effect of opioids and is particularly effective at reversing respiratory depression. Two other classes of drugs that act on the renin-angiotensin system, angiotensin-converting-enzyme inhibitors and angiotensin II receptor blockers. Immunohistochemical and ultrastructural localization of leptin and leptin receptor in human white adipose tissue and differentiating human adipose cells in primary culture. The RET proto-oncogene encodes a cell membrane receptor tyrosine kinase. Effects of BG9719, an A1-adenosine receptor antagonist, and furosemide on glomerular filtration rate and natriuresis in patients with congestive heart failure. The objective is to optimize Fc receptor mediated antibody function. Prokinetic effects of a ghrelin receptor agonist GHRP-6 in diabetic mice. He broke off, because one of the QCA men was bringing out a teep rod, a receptor that would pick up and record his thoughts for police inspection. Production of soluble transferrin receptor in K562 erythroleukaemia cells. Phosphorylation of focal adhesion vasodilator-stimulated phosphoprotein at Seri57 in intact human platelets correlates with fibrinogen receptor inhibition. It has a unique profile with two mechanisms of action, combining mu-opioid receptor agonism and noradrenaline reuptake inhibition properties in a single molecule. Some authors detecting estrogen receptor in condyloma acuminata by ImmunoHistoChemistry, found that positive ER was present in most of CA cases while a few in normal tissues. Knockout of luteinizing hormone receptor abolishes the effects of follicle-stimulating hormone on preovulatory maturation and ovulation of mouse Graafian follicles. Another major focus of his research has concerned receptor tyrosine kinases, a family of signaling proteins that control the clinical behavior of neuroblastomas. The response to non-depolarising muscle relaxants is potentiated due to increased receptor sensitivity so monitoring the train-of-four count and ratio is useful. Weaver's team found that cancer cells grown in a 3-D environment had higher levels of a protein called nuclear receptor corepressor 2 than cells in flat dishes. The bone morphogenetic protein receptor type 1A is a high-affinity receptor for members of the BMP family, which contribute to the development and remodeling of bone. Find more words! Another word for Opposite of Meaning of Rhymes with Sentences with Find word forms Translate from English Translate to English Words With Friends Scrabble Crossword / Codeword Words starting with Words ending with Words containing exactly Words containing letters Pronounce Find conjugations Find names From Afrikaans From Albanian From Amharic From Arabic From Armenian From Azerbaijani From Basque From Belarusian From Bengali From Bosnian From Bulgarian From Catalan From Cebuano From Chichewa From Chinese From Corsican From Croatian From Czech From Danish From Dutch From Esperanto From Estonian From Farsi From Filipino From Finnish From French From Frisian From Galician From Georgian From German From Greek From Gujarati From Haitian Creole From Hausa From Hebrew From Hindi From Hmong From Hungarian From Icelandic From Igbo From Indonesian From Irish From Italian From Japanese From Javanese From Kannada From Kazakh From Khmer From Korean From Kurdish From Kyrgyz From Lao From Latin From Latvian From Lithuanian From Luxembourgish From Macedonian From Malagasy From Malay From Malayalam From Maltese From Maori From Marathi From Mongolian From Burmese From Nepali From Norwegian From Polish From Portuguese From Punjabi From Romanian From Russian From Samoan From Scots Gaelic From Serbian From Sesotho From Shona From Sinhala From Slovak From Slovenian From Somali From Spanish From Sundanese From Swahili From Swedish From Tajik From Tamil From Telugu From Thai From Turkish From Ukrainian From Urdu From Uzbek From Vietnamese From Welsh From Xhosa From Yiddish From Yoruba From Zulu To Afrikaans To Albanian To Amharic To Arabic To Armenian To Azerbaijani To Basque To Belarusian To Bengali To Bosnian To Bulgarian To Catalan To Cebuano To Chichewa To Chinese To Corsican To Croatian To Czech To Danish To Dutch To Esperanto To Estonian To Farsi To Filipino To Finnish To French To Frisian To Galician To Georgian To German To Greek To Gujarati To Haitian Creole To Hausa To Hebrew To Hindi To Hmong To Hungarian To Icelandic To Igbo To Indonesian To Irish To Italian To Japanese To Javanese To Kannada To Kazakh To Khmer To Korean To Kurdish To Kyrgyz To Lao To Latin To Latvian To Lithuanian To Luxembourgish To Macedonian To Malagasy To Malay To Malayalam To Maltese To Maori To Marathi To Mongolian To Burmese To Nepali To Norwegian To Polish To Portuguese To Punjabi To Romanian To Russian To Samoan To Scots Gaelic To Serbian To Sesotho To Shona To Sinhala To Slovak To Slovenian To Somali To Spanish To Sundanese To Swahili To Swedish To Tajik To Tamil To Telugu To Thai To Turkish To Ukrainian To Urdu To Uzbek To Vietnamese To Welsh To Xhosa To Yiddish To Yoruba To Zulu English French Afrikaans Word Albanian Word Arabic Word Bengali Word Chinese Word Croatian Word Czech Word Danish Word Dutch Word English Word Finnish Word French Word German Word Greek Word Hindi Word Hungarian Word Icelandic Word Indonesian Word Italian Word Japanese Word Korean Word Latin Word Malay Word Malayalam Word Marathi Word Nepali Word Norwegian Word Polish Word Portuguese Word Romanian Word Russian Word Serbian Word Slovak Word Spanish Word Swahili Word Swedish Word Tamil Word Telugu Word Thai Word Turkish Word Ukrainian Word Uzbek Word Vietnamese Word Welsh Word All words 2-letter words 3-letter words 4-letter words 5-letter words 6-letter words 7-letter words 8-letter words 9-letter words 10-letter words 11-letter words 12-letter words 13-letter words 14-letter words Plural of Singular of Past tense of Present tense of Verb for Adjective for Adverb for Noun for Meaning of name Origin of name Names meaning Names starting with Names of origin receptor Use * for blank tiles (max 2) Advanced Search Advanced Search Use * for blank spaces Advanced Search Advanced Word Finder See Also What is another word for receptor? What is the opposite of receptor? Words that rhyme with receptor What is the plural of receptor? What is the adjective for receptor? What is the noun for receptor? Use our Sentence Generator Nearby Words receptivity receptive to receptiveness receptively receptive receptions receptors recertification recertify recess recessed recesses 8-letter Words Starting With r re rec rece recep recept recepto