Physicians who were addicted to opioids most commonly used pharmaceutical opioids, with very few using heroin. |
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Patients with a past or present history of addiction or dependence on opioids account for the majority of these reports. |
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Some opioids are natural compounds derived from opium, others are synthetic medications that work in a similar way. |
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Heroin overdosage commonly occurs when higher potency heroin is used or when the heroin is mixed with other opioids, such as fentanyl. |
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Historical evidence suggests that law enforcement has been useful in the control of alcohol, tobacco, amphetamine, and opioids. |
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In this study, opioids, other psychoactive medications and dehydration were the most frequent causes of reversible delirium. |
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As a result, pharmaceutical companies have produced alternative opioids such as oxycodone, hydromorphone, fentanyl, methadone, and tramadol. |
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For severe intractable cancer pain, more potent long-acting opioids are recommended. |
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The stimulators work either by blocking sympathetic nerve fiber transmission or by releasing endogenous opioids with stimulation. |
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Within these two therapeutic drug classes, penicillins were identified 22 times, cephalosporins 21 times, and opioids 20 times. |
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Thus, the researchers proposed the hypothesis that alcohol releases endogenous opioids and that naltrexone blocks the opioid receptor. |
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Patients who are dependent on opioids or benzodiazepines may require detoxification from these substances as well. |
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Hypoxia increases central nervous system levels of specific neuroinhibitors such as endogenous opioids, adenosine, and gamma-aminobutyric acid. |
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Phenothiazines, tricyclic antidepressants, and CNS depressants may potentiate the therapeutic and adverse effects of opioids. |
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There is no evidence that muscle relaxants or opioids are more effective than these medications, although they may be useful in certain cases. |
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However, women who are dependent on opioids do better with methadone than with no treatment. |
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Some of the most addictive pain medications are opioids, a family of drugs that have effects similar to those of opium or morphine. |
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First, physicians tend to be concerned about using opioids in terminal patients for fear of suppressing respiration and hastening death. |
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Those results are not out, but from what I hear from some of the researchers, there are going to be remarkable results in the use of opioids. |
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Because it is taken orally, it can eliminate or reduce the sharing of needles to inject opioids. |
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Two major classes of medications, benzodiazepines and opioids, are of significant concern when utilized to help manage chronic pain. |
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Changes that have been observed in association with chronic administration of opioids include physical atrophy of dopamine-producing neurons in the ventral tegmental area. |
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Nitrous oxide, sometimes used during dental procedures, affects the opioids. |
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Opioids such as methadone and buprenorphine are used to treat addiction to other opioids, such as heroin. |
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You can die by taking street methadone by itself-but it is especially dangerous to take it with other opioids, alcohol or tranquillizers. |
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Codeine or other opioids may obscure signs on which to judge the diagnosis or clinical course of patients with acute abdominal conditions. |
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This means it acts more slowly in the body, for a longer period of time, than most other opioids. |
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Instead of lessons about the dangerous, addictive, and deadly qualities of prescription opioids, he got lessons on relieving pain. |
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The risk of overdose increases if you take OxyContin with other opioids, alcohol or tranquillizers. |
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Some people inject opioids to increase the intensity of the euphoric effect. |
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Frequently used pharmacologic therapies include nonsteroidal anti-inflammatory medications, muscle relaxants, opioids and other analgesics, and antidepressants. |
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Giving opioids to supplement analgesia, followed by conversion to general anaesthesia, was a perfectly reasonable response by the anaesthetist to Weir's distress at delivery. |
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Another approach is using drugs to antagonise the peripheral effects of opioids so that bowel dysfunction is reversed, speeding discharge from hospital. |
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Penalties for the illicit possession and distribution of opioids range from fines to life imprisonment. |
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The most common drug abuse disorders involved marijuana, followed by cocaine, amphetamines, hallucinogens, opioids, sedatives, tranquilizers, and inhalants. |
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Constipation: Practically all patients become constipated while taking opioids on a persistent basis. |
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And 9,869 people died from prescription opioids in 2012, a decrease from 2011, back to 2008 levels. |
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Similarly in the Oceania region, only a third of opioids users consume heroin. |
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If appropriate dosages of a tricyclic antidepressant or gabapentin do not provide adequate relief, strong opioids such as oxycodone, morphine, or methadone may be required. |
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The lethal dose is even less if taken together with other opioids, alcohol, benzodiazepines or barbiturates. |
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Low doses of opioids suppress the sensation of pain and the emotional response to pain. |
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Short-acting opioids such as heroin must be taken frequently to avoid withdrawal. |
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Pruritus may also be due to activation of neural systems as opioids that do not release histamine also cause pruritus. |
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It also warns about reducing the dosage if the patient uses narcotic pain relievers or other opioids or sedatives. |
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Opioid use may directly impinge on vocational rehabilitation because some occupations ban the use of opioids even for medicinal purposes. |
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Further research is now vital to determine how much opioids harm babies, and what can be done to curb America's growing taste for them. |
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Codeine and other opioids act on the brain stem respiratory centers reducing their responsiveness to increases in carbon dioxide tension, resulting in respiratory depression. |
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The term usually refers to opiates or opioids, which are called narcotic analgesics. |
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Severe pain antagonizes the respiratory-depressant effects of opioids. |
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In the coming years, this challenge is expected to be magnified in markets such as the U. S. where opioids are expected to increase their share of the overall pain treatment market. |
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In the presence of head injury or other intracranial lesions, the respiratory depressant effects of codeine and other opioids may be markedly enhanced, as well, as their capacity for elevating cerebrospinal fluid pressure. |
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So, for example, as for thefts of opioids in Canada, the most commonly stolen opioid in Canada, at least at the time we looked at this data, was in fact combinations of codeine and acetaminophen. |
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Mild opioids, such as codeine, given up to an hour before a procedure may ease the pain, and will continue to provide relief for some time after the event. |
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Switching opioids allows the body to clear out the previous medication. |
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Despite almost universal acceptance in acute and cancer pain treatment, opioids have been avoided for treating chronic nonmalignant pain. |
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We realized that our SCI patients were overmedicated with muscle relaxants, pain killers, opioids, and sedatives. |
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Patients known to be hypersensitive to other opioids, antihistamines or sympathomimetic amines may exhibit cross sensitivity to hydrocodone, pyrilamine or phenylephrine. |
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An additional way of classifying opioids analgesic drugs is on the basis of their histamine releasing capacities. |
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The respiratory depressant effects of opioids include carbon dioxide retention and secondary elevation of cerebrospinal fluid pressure, and may be markedly exaggerated in these patients. |
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People who are on certain medications, such as opioids to manage pain or shortness of breath, will definitely need laxatives to keep their bowels moving. |
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Short-term effects of opioids include, among others: nausea and vomiting, drowsiness, apathy, slowed and slurred speech, lack of concentration, and euphoria. |
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If there is any pain, restlessness or shortness of breath, they can be controlled with medications such as opioids, sedatives or medications for anxiety. |
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Caregivers may also use less benzodiazepines and opioids if there is a decreased level of consciousness leading to withdrawal states which often present as agitation or anxiety. |
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His clinical research has been primarily in the area of delirium, the use of methadone and equianalgesic dosing ratios of opioids, and spiritual care. |
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As with other opioids, tolerance and physical dependence may develop upon repeated administration of Targin and there is a potential for development of psychological dependence. |
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Physicians should not let concerns of physical dependence deter them from using adequate amounts of opioids in the management of severe pain when such use is indicated. |
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No drug has been found that can match the painkilling effect of opioids without also duplicating much of their addictive potential. |
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Nicotine scores almost as highly as opioids on drug effect questionnaire liking scales, which are a rough indicator of addictive potential. |
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The illness, called neonatal abstinence syndrome, is a drug withdrawal syndrome that most commonly occurs after in utero exposure to opioids. |
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Therapeutically, opioids are used to provide analgesia, as antitussives, and to treat symptoms of diarrhea. |
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Extended-release and long-acting opioids indude hydromorphone, morphine, oxycodone, oxymorphone, and tapentadol. |
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Both propofol and opioids have been shown to suppress central tonic outflow to the genioglossus muscle, which is the primary airway dilator. |
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The CDC estimates that 46 Americans die each day from overdose on opioids. |
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Federal laws regulate the possession and distribution of all opioids. |
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Unfortunately, one of the barriers to effective pain management is that the governing body of doctors still frowns on the prescription of strong pain medicine, especially opioids. |
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The 1990s saw a big increase in prescriptions of opioids for chronic pain. |
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That, in turn, could allow athletes like Mr El Guerrouj to train longer and harder. The reason is almost certainly the effects of endogenous opioids, better known as endorphins. |
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But our strong love shall not its power lose While opioids keep us on the straight and narrow While oxytocin does its magic prove And vasopressin binds us one to other. |
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Tolerance as well as both physical and psychological dependence may develop upon repeated administration of opioids, and are not by themselves evidence of an addictive disorder or abuse. |
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Propofol sedation for outpatient endoscopy has become a popular technique in place of midazolam and opioids, although the combination technique still has its proponents. |
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Because the lethal dose of heroin was viewed as a hundred times greater than its effective dose, heroin was advertised as a safer alternative to other opioids. |
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The main classes of painkillers are NSAIDs, opioids and Local anesthetics. |
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Naloxone, an opioid receptor antagonist, quickly and powerfully reverses the effect of opioids and is particularly effective at reversing respiratory depression. |
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Movantik belongs to a class of drugs called peripherally acting opioid receptor antagonists, which are used to decrease the constipating effects of opioids. |
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If converting from opioids other than morphine, calculate the equipotent morphine dose for the current analgesic and use this dose to convert to the new opioid. |
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