How to use metastatic in a sentence

Looking for sentences and phrases with the word metastatic? Here are some examples.

Sentence Examples We do not know whether the tumor in the bone marrow represents a primary or metastatic process. Prior radiation therapy was acceptable, but prior chemotherapy for metastatic disease was not allowed. The risk for developing metastatic lesions from primary cutaneous melanomas increases with tumor thickness. Plain radiographs are less sensitive for metastatic lesions than are other imaging tests. A metastatic work-up, including a bone scan and a computed tomographic scan of the thorax and abdomen, was negative. The brain lesion was subsequently biopsied and diagnosed as metastatic adenoid cystic carcinoma. The differential diagnosis includes lymphoma, granulomatous infections, benign vascular tumors, and metastatic cancer. This process is fundamental in the development, progression, and metastatic spread of solid tumors. Brain metastases occasionally produce psychological symptoms before metastatic disease is discovered. Ocular melanoma metastatic to other sites generally occurs in association with liver metastases. Meningeal spread is not uncommon in cases of intracranial gliomas or metastatic carcinoma. The echocardiography and the pathologic examination revealed a metastatic melanoma. Bisphosphonates reduce skeletal morbidity in cancer patients with metastatic bone disease. My wife received post-operative chemotherapy from these medical oncologists, seven months after having that metastatic tumour surgically excised. Epidural spinal cord compression from metastatic cancer is common and serious but potentially treatable. As primary bone tumors are rare in toddlers, search for a primary tumor metastatic to bones is needed. The mother had an aggressive metastatic disease, and the cancer could have spread across the placenta to the fetus. General examination to exclude generalised lymphadenopathy or metastatic disease should then be undertaken. We defined advanced stage as nodal or metastatic spread and high grade as poorly differentiated, undifferentiated, or anaplastic disease. The differential diagnoses include dermatofibroma, keloid, Kaposi's sarcoma and metastatic carcinoma. Show More Sentences There was no evidence of inflammation, infection, or metastatic neoplasia in the patients dura. This patient's history and presentation are rather typical for a sarcoma or metastatic carcinoma but not so much for a lymphoma. The mammographic size of a palpable metastatic lesion corresponds closely with the size on physical examination. One patient who had undergone a nondiagnostic CT fluoroscopy-guided TBNA proved to have a metastatic spindle cell sarcoma at surgery. Unlike carcinomas, metastatic sarcomas generally occur deeper and may not ulcerate the mucosa. His professional interests were in metastatic paraplegia and paediatric orthopaedics. The angiographic findings in a case of metastatic meningeal carcinomatosis and a case of primary meningeal sarcomatosis are presented. Patients with metastatic disease are often cachectic and rarely survive more than a few weeks. These tumors are highly aggressive, with most deaths related to hepatic failure, massive hemorrhage, or metastatic disease. The patient refused additional metastatic workup, chemotherapy, and radiotherapy. Four weeks later, a computed tomography scan showed spontaneous regression of some of the metastatic lesions. The differential diagnosis included metastatic lymphoma, epidural abscess, hematoma, and vascular malformation. Among the neoplastic lesions, both primary and metastatic malignancies must be considered. Patients with this malignancy most often present with a cervical mass from metastatic spread to a lymph node. None of the 3 metastatic carcinomas to the liver expressed either of these adhesion proteins. Hodgkin's lymphoma and most metastatic carcinomas typically progress through nodes in anatomic sequence. Salient autopsy findings included metastatic adenocarcinoma of peripancreatic lymph nodes and diffuse leptomeningeal carcinomatosis. If metastatic disease was suspected, the area was surgically excised for histologic examination. When they told us she had metastatic disease, she was well schooled in what to expect, and she expected two years. We report a case of recurrent prostate adenocarcinoma presenting as bowel obstruction due to widespread metastatic disease in the omentum and peritoneum. Show More Sentences This type of metastatic spread can present as cryptogenic liver failure. Miyao et a 116 studied 14 patients with lymph node metastases from bladder cancer and found complete concordance between genetic defects in the primary and metastatic sites. In patients with metastatic disease that does not respond to radiotherapy or chemotherapy, immunotherapy may offer an additional form of cancer control. After receipt of the pathology report, computed tomograms of the chest, abdomen, and pelvis showed no other lesions or evidence of metastatic disease. Larger splenic metastatic lesions were more often symptomatic. Underlying conditions were more common among patients than in the control group, particularly AIDS related illness, metastatic cancers, and lymphomas or leukaemia. Two helpful tips the authors present are that lymphangitic streaking is often consistent with cutaneous infection, and that splenomegaly is rare in metastatic cancer. The adrenals are the fourth most common location for metastatic disease. The patient received palliative radiation to the neck and systemic chemotherapy, but she died of widely metastatic disease approximately 2 years after the thyroidectomy. Of the 9 metastatic melanomas, 5 were melanotic and 4 were amelanotic. From there grew the idea that inflammation itself could be a facilitator of metastatic growth. This suggests that pleural carcinomatosis represents a final common pathway in metastatic disease, and may not, in and of itself, be indicative of a poor prognosis. It will collect outcome data for patients with metastatic breast cancer receiving everolimus with another drug, exemestane. Patients with nonresectable locally advanced or metastatic disease received chemotherapy with or without radiotherapy. If the cancer is metastatic, then there might be other symptoms depending on the site of the original cancer. Highly malignant MSDACs that were derived from metastatic sites exhibited CSC status and exerted robust tumorosphere formations ex vivo. Wild-Type KRAS is required for panitumumab efficacy in patients with metastatic colorectal cancer. Findings in the deep lobe of the left parotid node were consistent with rhabdomyosarcoma metastatic to the lymph nodes. Oxaliplatin added to the simplified bimonthly leucovorin and 5-Fluorouracil regimen as second-line therapy for metastatic colorectal cancer. Lupron and Zoladex were largely prescribed for cohort patients with metastatic prostate cancer. Show More Sentences Possible involvement of bone morphogenetic protein 2 in heterotopic ossification in metastatic lesion from urothelial carcinoma of bladder. The radiological appearance of diffuse nodular type of BAC may be confused with miliary tuberculosis and pulmonary metastatic nodules. The combination of capecitabine and docetaxel is currently used to treat HER2-negative, anthracycline-resistant metastatic breast cancer. Valerie has been diagnosed with leptomeningeal carcinomatosis, which is very rare and usually a secondary or metastatic cancer. Deregulation of Wnt and other mitogenic pathways results in formation of aggressive tumours with metastatic potential. Biopsy of the lesion revealed a well-differentiated metastatic mucinous adenocarcinoma of the colloid type. Spontaneous pneumothorax is a rarely seen complication in metastatic pulmonary diseases. Efficacy of sunitinib and sorafenib in metastatic papillary and chromophobe renal cell carcinoma. Some types of primary or metastatic tumours can also affect just one of the nerves anywhere along their extra-cerebral course. Choriocarcinoma is a malignant tumor derived from trophoblasts that has high metastatic potential. We describe a case where EBUS-TBNA was pivotal in reducing the number of invasive procedures in a patient with metastatic supraglottic carcinoma. The trial is evaluating Zymafos, or palifosfamide, as a treatment for patients with unresectable or metastatic soft-tissue sarcoma. Men who have undergone orchiectomy require extended follow-up surveillance because of the delayed metastatic potential of these tumors. This case report provides evidence of metastatic spread to the paranasal sinuses. German cancer research on metastatic thyroid conditions found that 5 of 10 patients survived more than 3 years with dendritic cell therapy. Lightfix clinical trial for the treatment of impending and pathologic fractures in the humerus due to metastatic carcinoma. Hematospermia as the presenting symptom of metastatic malignant melanoma of unknown primaiy origin. A total of 65 patients, with histologically confirmed metastatic colon adenocarcinoma of the liver, were evaluated. Preleukemia following large dose radioiodide therapy for metastatic thyroid carcinoma. Etoposide and cisplatin chemotherapy for metastatic good-risk germ cell tumors. Show More Sentences Prurigo nodularis as initial presentation of metastatic transitional cell carcinoma of the bladder. Primary Ewing sarcoma of the orbit and metastatic Ewing sarcoma to the choroid of the eye have been previously reported. In cancer, the glycocalyxes of circulating tumor cells play a fundamental role in the metastatic process. Often, cancer metastasizes to the lungs and liver so metastatic tumor cells as well as primary tumor cells may be seen in exudative effusions. Isogeneic comparison of primary and metastatic lung cancer identifies CX3CR1 as a molecular determinant of site-specific metastatic diffusion. There are Holocene cases that include multiple myeloma, metastatic carcinoma, nasopharyngeal carcinoma, and benign osteoma. Less commonly encountered masses include renal lymphoma, fat-poor angiomyolipoma, multilocular cystic nephroma, oncocytoma, and metastatic disease. Herceptin alone is approved for the treatment of HER2-positive mBC in patients who have received one or more chemotherapy regimens for metastatic disease. The presence of a metastatic papillary carcinoma in the neck is presumptive evidence of a primary thyroid neoplasm since neck metastases of other primary tumors are uncommon. Recurrent metastatic breast carcinoma presenting with pansinusitis and choroidal metastases and subsequent bilateral simultaneous orbital cellulitis. Chief diagnostic considerations were a primary central nervous system neoplasm such as astrocytoma, hemangioblastoma, or ganglioglioma, rather than metastatic disease. Pathology revealed metastatic poorly differentiated adenocarcinoma consistent with ovarian cancer involving the diaphragm, liver, and visceral pleura. At this time, metastatic infections, retroperitoneal and subphrenic infections, and osteomyelitis of the spine and ribs seldom lead to mediastinitis. Abdominal ultrasonography revealed a 3 x 4 cm subcapsular lesion in the left lobe of the liver, highly suspect for metastatic spread of an unknown tumor. She had recently completed her second round of folinic acid, fluorouracil, and oxaliplatin therapy for metastatic colon cancer and was neutropenic. The TMA also included 1 case of metastatic chromophobe RCC and 1 case of unclassified RCC with matched primary tumor and metastasis, which showed no EZH2 labeling. Spontaneous pneumothorax is a well-recognized pulmonary complication of a wide variety of disorders, ranging from endometriosis to metastatic malignancy. The value of anti-calretinin antibody in the differential diagnosis of normal and reactive mesothelia versus metastatic tumors in effusion cytology. Selye concluded that unlike the case with simple metastatic calcifications, this response occurred only with the use of a sensitizer and a challenger. Preoperative workup for metastatic breast disease, including radiographs of the thorax, liver ultrasound, bone scintiscans, and blood markers were all negative. Show More Sentences Lymphoedema is a chronic condition occurring in some metastatic cancers and is found in around five to 10 per cent of all new palliative patients. We could not plan a new high-dose RAI treatment because the metastatic tumor was unresponsive to radioiodine and her health condition was not suitable for this treatment. It was first described by von Herbay et al, who identified fibrocellular proliferation of the intima of small pulmonary arterial vessels in patients with metastatic carcinoma. Early retrospective studies have shown correlation between the metastatic behavior among histologically ambiguous melanocytic lesions and the FISH results. Examples from Classical Literature Primary cancer occurs most frequently, metastatic cancer with great rarity. In this condition the pancreas may be the seat of either acute parenchymatous inflammation or of metastatic abscesses. Virchow49 had always maintained the possibility of regarding tuberculosis as a heteroplastic or metastatic scrofula. Melanotic sarcoma may occur as metastatic from an original melano-sarcomatous tumor of the skin or eyeball. Flat-celled epithelioma is found at the cardiac orifice and as a metastatic growth in other parts of the stomach. A second form of metastatic arthritis is met with in strangles. Oral metastatic tumors usually begin as painless soft-tissue nodules growing from the mandible. Find more words! 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What is the opposite of metastatic? Words that rhyme with metastatic What is the adverb for metastatic? What is the adjective for metastatic? What is the noun for metastatic? Use our Sentence Generator Nearby Words metastasizing metastasized metastasize metastasise metastasis metastases metatarsal metatarsalgia metatarsals metatarsus metate metathesis 10-letter Words Starting With m me met meta metas metast metasta metastat metastati