How to use metastases in a sentence

Looking for sentences and phrases with the word metastases? Here are some examples.

Sentence Examples Patients with certain rare tumours, such as liver metastases from neuroendocrine disease and sarcomas, can do well for several years. More extensive staging revealed multiple vertebral lesions consistent with metastases, but no spread to abdominal viscera was visualized. No effect was observed on visceral sites of metastases, although reassuringly no trend toward an increase was identified. Laparoscopy is used to examine the parietal peritoneum, liver, and other metastases of the viscera. The diagnosis was revised to carcinoma of the lung with metastases to the adrenals. Oxaliplatin will be given only to patients who have liver metastases that may be shrunk to operable size. Brain metastases occasionally produce psychological symptoms before metastatic disease is discovered. The visible portions of the liver and adrenals were negative for metastases. The therapeutic value is controversial but would be limited to patients with nodal metastases. A computed tomographic scan showed several osteoblastic and osteolytic lesions in vertebral bodies and the pelvis, compatible with metastases. Because of the protective layer of the dura mater, subdural and intraparenchymal metastases from prostate cancer are rare. A whole-body bone scan showed no evidence of bony metastases, and a mammogram showed no evidence of malignancy. We report a case in which cutaneous metastases from a melanoma imitated herpes zoster. The case of Paget disease with ductal carcinoma in situ had no nodal metastases. There were several small distant metastases in the upper lobe of the same lung and in the opposite pleura or subpleural lung parenchyma. Most centres in the United Kingdom recommend computed tomography of the chest to pick up synchronous early lung tumours or metastases. Lung metastases in the absence of liver metastases are usually explained by this mechanism. Patients with peripheral tumors with or without metastases to hilar nodes are usually treated with surgical lobectomy or pneumonectomy. One must exclude metastases from carcinoids of more typical sites of origin. These findings were thought to be consistent with carcinoid tumor with metastases to the liver. Show More Sentences Ocular melanoma metastatic to other sites generally occurs in association with liver metastases. Nuclear medicine scintigraphy can image the entire axial and appendicular skeleton to detect distant sites of osseous metastases. All patients underwent cystectomy for bladder cancer and had regional lymph node metastases at the time of surgery. The most common sites of tumor metastases are the lymph nodes in the mediastinum. Liver metastases frequently present with multiple hepatic lesions on diagnosis. Only 10 to 15 percent of hepatic metastases and up to 15 percent of hepatocellular carcinomas are surgically resectable. Overall, late metastases to the spleen were seen more often in melanomas, choriocarcinomas, and breast carcinomas. Common sites of metastases include liver, bone, bone marrow, extradural space, orbits and skin. The skull is a frequent site of bone metastases, which commonly present as proptosis and periorbital ecchymoses. With the exception of liver metastases of colorectal cancer, tumour deposits are almost always multiple and seldom amenable to resection. The iliac crest bone marrow biopsy is the gold standard for detecting of bone marrow metastases in small cell lung cancer. Computed tomography of the abdomen and lung immediately before her death showed liver and lung metastases. Some 30 per cent of patients present with palpably enlarged nodes containing metastases. These tumors tend to have lymph node metastases as seen in papillary carcinoma rather than hematogenous spread. Osteoporosis, metastases, myeloma, and aggressive vertebral haemangioma can all cause vertebral body collapse and spinal pain. Interestingly, contrast enhanced computed tomography identified liver metastases in only three of the 17 patients. Most patients in clinical trials had osteolytic bone metastases on imaging studies. Four patients responded despite extensive metastases to liver, brain, skin, and adrenals, with survival of 4 to 6 months. However, pleural metastases may appear identical to malignant mesothelioma, characterized by diffuse pleural thickening and encasement of the underlying lung. Miyao et a 116 studied 14 patients with lymph node metastases from bladder cancer and found complete concordance between genetic defects in the primary and metastatic sites. Show More Sentences The metastases are well delineated after 20 days but not definitely visible beforehand. The number of lymph nodes with metastases also has prognostic importance. They are a frequent cause of death from hemorrhage, shock or septic metastases, ischemia and major amputation. The HIFU technique makes it possible to destroy hepatic metastases with precision, while sparing the neighboring anatomic structures. However, since no autopsy was performed, these findings alternatively could have arisen from other diseases, including brain metastases or Bell's palsy. It spreads from the benignant disease uncomplicated partial mole to the most malignant choriocarcinoma in stage IV of disease with brain metastases. Non-resectable cancers, and those with metastases, are advanced malignancies with a similar prognosis. The effect of injection of B16F10 cells, pretreated with jara and jari, on allograph tumor growth and metastases in vivo was also investigated. Lytic bone metastases in cancer patients are caused by increased osteoclast activity. Other findings such as dilated bile ducts, regional adenopathy, or hepatic metastases may be seen. Dosing recommendations differ for tumour-induced hypercalcemia, lytic bone metastases and multiple myeloma, and Paget's disease. The study did permit palliative procedures such as transurethral resection of the prostate and irradiation for painful bone metastases. Stage II are patients with retroperitoneal lymph node invasion but no visceral metastases, with or without raised tumour markers. When used in combination with standard anticancer treatment, pamidronate disodium led to a delay in progression of bone metastases. Raised concentration in blood serum are particularly found in prostatic cancer, bone metastases of cancer and various bone diseases. Although metastases are rare, the cancer may spread locally and invade surrounding tissues. About 10 percent of persons with cancer have signs and symptoms that are not directly related to the location of a tumour or its metastases. These women are more likely to develop distant metastases and, therefore, may be at greater risk of dying from their disease. The location of the primary tumor and of any metastases determines many of the possible symptoms. This is crucial since in most cancers it is not the primary tumor that kills the patient but rather the metastases. Show More Sentences The tumor or the metastases can create pressure or an obstruction in an area, which produces pain. Stimulation of ErbB2 is associated with cell proliferation, tumour progression and the development of metastases. This assessment should be extended to include the liver, the brain and the bones, which are the three areas targeted by metastases. When the cancer has spread outside the prostate, i.e. to other organs, the new tumors are referred to as metastases. A small number of patients with bony metastases have developed hypercalcaemia on initiation of therapy. Early identification and attention to bone metastases can help proper treatment. In addition, testicular lymphoma and metastases from other primary tumours have been reported. We redetermine the role of symptoms and serum concentrations in detecting bony metastases in lung cancer and reassess the accuracy of bone scans for screening. Delirium and dementia may arise from brain metastases, which usually originate from lung cancer but also from tumours of the breast and alimentary tract and melanomas. This injection also identifies the lymphatic basins, nodal areas, and respective lymph draining sites that are considered to be at risk for metastases. The patient's medical history was significant for grade 4 osteosarcoma, telangiectatic variant, of the left femur at the age of 6 years, with bilateral lung metastases. Six hundred and eight additional liver computed tomograms detected only one asymptomatic patient with liver metastases who might have benefited from liver resection. The liver is one of the most common sites for metastases from carcinoma. Five cases represented metastases from cutaneous squamous carcinomas. It is essential to confirm the diagnosis and determine whether cervical lymph nodes are involved or there are other primary tumours or metastases. Ten cases demonstrated durai metastases, and 3 cases showed focal leptomeningeal involvement. cases of diffuse leptomeningeal carcinomatosis were excluded. Splenic metastases associated with melanomas, choriocarcinomas, and breast carcinomas were often detected long after primary tumors were diagnosed. The patient continued to develop further skeletal metastases with pathological fractures and finally died ten months after the initial presentation. The recommended dose of Pamidronate Disodium for Injection for the treatment of predominantly lytic bone metastases and multiple myeloma is 90 mg administered as a single infusion every 4 weeks. The two leiomyosarcoma cases presented with lung metastases at the time of diagnosis, and 1 patient died of the disease at 7th month. Show More Sentences As metastases need to be treated according to their primary origin, accurate identification of the metastases' primary origin can be critical for determining appropriate treatment. Do adrenal metastases from lung cancer develop by lymphogenous or hematogenous route? Bone morphogenetic protein 7 in the development and treatment of bone metastases from breast cancer. Benign tumours, usually schwannomas on the vestibulocochlear nerve, may compress the cerebellum and lead to dysfunction on one side, but malignant astrocytomas and metastases from cancers are more common. Large darkish metastases spreading over the whole of the lower limb. Osteolytic bone metastases in breast carcinoma pathogenesis, morbidity and bisphosphonate treatment. The study confirmed a significant benefit for Femara versus tamoxifen in reducing the risk of distant metastases and the overall risk of breast cancer recurrence. Pamidronate prevents skeletal complications and is effective palliative treatment in women with breast carcinoma and osteolytic bone metastases. Tumors that contain RAS mutations have been associated with tumor dedifferentiation, distant metastases, and a poorer survival rate. First, Procyon demonstrated the efficacy of PCK3145 in reducing tumor volume and delaying the development of skeletal metastases in an animal model of prostate cancer. Neoplastic processes that can enlarge the stalk include lymphoma, metastases, germinoma and teratoma. On imaging studies, the liver metastases of GCTs are characterized by thickened walls with hypervascularity and nodular excrescences. In principle, resection of liver metastases is indicated when an extrahepatic recidivous occurrence or a second tumour is excluded. This new edition features extensive updates of radiobiology, physics and techniques, and an entire new section on spine metastases. The investigators tested reovirus in vitro against recently resected colorectal cancer liver metastases. It is possible that the severity and incidence of cerebral effects increase with the administration of high doses, the presence of brain metastases, or advanced cerebral arteriosclerosis. Twenty-nine patients had visceral metastases, and 27 patients underwent surgery including radical cystectomy and nephroureterectomy. The recommended dose for prevention of skeletal events in patients with breast cancer and bone metastases is 6 mg intravenous injection given every 3-4 weeks. In tumour-induced hypercalcemia, pamidronate disodium normalizes plasma calcium between 3 and 7 days following the initiation of treatment irrespective of the type of malignancy or presence of detectable metastases. The case was reevaluated and reconsidered as a primary palatine tonsillar achromic melanoma with concomitant pigmented gastric and ileal metastases. Show More Sentences Other rare presentations of seminomas include cutaneous and perineal metastases, in addition to paraneoplastic syndromes including polycythaemia. Prevention of the progression and dissemination of existing metastases, as well as the formation of new skeletal metastases has been demonstrated both by scintigraphy and by radiography. This represents a promising therapeutic option for patients with isolated and resectable liver metastases which has been highlighted in the ASCO Press Conference. Pharmacological ascorbic acid suppresses syngeneic tumor growth and metastases in horrnone-refractory postate cancer. Soft-tissue metastases from oropharyngeal cancers are rare, however, particularly when they present in the absence of widespread metastasis. The rate of regional PTC metastasis to the neck is relatively high, while metastases outside the deep cervical chain are rare. Photodynamic therapy for endobronchial metastases from non bronchogenic primaries. Bone metastases may manifest themselves as pain, which may often be described as generalized deep pain, radiating pain, tingling, numbness, achy bones, or muscles pain-including back pain. Multifocal FDG-avid hepatic metastases were also identified, as well as extensive serosal, peritoneal, mesenteric, and omental carcinomatosis. The absence of any histological sign of malignity in the primary tumor and in the metastases, as observed in our patient, is remarkable. In a patient with cancer, if a lesion on a bone scan is normal on X-ray, bone metastases are unlikely. It has limited ability to detect metastases in retroperitoneal and retrocrural lymph nodes and is usually unable to detect extradural extension of tumors. Recurrent metastatic breast carcinoma presenting with pansinusitis and choroidal metastases and subsequent bilateral simultaneous orbital cellulitis. Additionally, among patients who have frequent recurrences and metastases, spontaneous regressions occurred at all tumor locations simultaneously. Tumors and metastases may arise as small avascular masses that subsequently induce the angiogenic ingrowths that are required to allow for further growth of early tumors. The differential diagnosis of such a radiographic picture includes giant cell tumour, osteolytic metastases, plasmacytoma, aneurysmal bone cyst and cystic neurofibromas. Late metastases of a hypernephroma to the thyroid and the pancreas. After the fourth passage the rats developed peritoneal carcinomas with metastases to the upper abdomen and peritoneal endotheliomas with focal infiltration. Prostate cancer cells have an exquisite tropism for bone, which clinically translates into the highest rate of bone metastases amongst male cancers. In conclusion, initial surgery approach, tumor size, extrathyroid invasion, lymph node metastases, and pathological type may be related to PTC recurrence. Show More Sentences Bone metastases from prostate cancer are often radiosensitive and most men will experience partial or complete pain relief from external beam radiation to a specific lesion. The presence of a metastatic papillary carcinoma in the neck is presumptive evidence of a primary thyroid neoplasm since neck metastases of other primary tumors are uncommon. Examples from Classical Literature Reinbach has found them in a case of lymphosarcoma with metastases in the bone-marrow. Peritoneal metastases were also noted in the pelvis and adjacent to the left kidney and right suprarenal region. Find more words! 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Words that rhyme with metastases What is the adverb for metastases? What is the adjective for metastases? What is the noun for metastases? Use our Sentence Generator Nearby Words metastable metastability metasomatism metasomatic metasoma metasilicate metastasis metastasise metastasize metastasized metastasizing metastatic 10-letter Words Starting With m me met meta metas metast metasta metastas metastase