| One patient did not respond due to faecal impaction but subsequently experienced laxation after manual disimpaction. |
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| There were no statistically significant differences between methylnaltrexone and placebo in the use of rescue therapies, enemas or disimpaction. |
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| Management involves prevention of constipation, aggressive fecal disimpaction, and occasionally surgical intervention. |
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| This study confirms that PEG-based agents are also effective for faecal disimpaction. |
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| In extreme circumstances, enemas or manual disimpaction may be needed. |
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| Endoscopic disimpaction is the treatment of choice for food impaction. |
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