Finally, all the Ames test strains have defective polysaccharide outer coats, to make them more permeable to the test chemicals. |
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Mutants that grew on these plates were judged to be defective in glucose metabolism and were not studied further. |
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The horse escaped from its stable during the night into the field and thence onto the railway line via a defective fence. |
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In accordance with the terms of this limited warranty, the company, at its expense shall repair or replace the product which is proven defective. |
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Since unmodified Ebola enters through, and attacks, the lungs, defective lung cells could benefit most from therapy based on this discovery. |
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But it has been proved that actually defective vehicles have contributed to accidents on Zambian roads. |
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In short, the vertebrate eye is a masterpiece not of design, but of jury-rigged compensations for a fundamentally defective architecture. |
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Once the grafts had matured they were used to reconstruct defective windpipes in seven foetal lambs. |
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If there is a bad set of specifications and a bad set of materials no good workman can fix the problem, because it is intrinsically defective. |
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Vehicles with worn or defective shock absorbers are less stable and more liable to go out of control. |
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The second major category of error is that of defective identification of patient, tissue, or laterality. |
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This defective recovery of DNA replication suggests an inability to coordinate lesion bypass or to initiate new replicons. |
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This could involve the expression in a yeast mutant, which is defective for an analogous transport system. |
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Once the buyer has shown goods to be defective, strict liability arises for their consequences. |
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A further 16 charges, relating to driving with a defective speed limiter, were found proven. |
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It is also thought by some authorities that bottle-fed babies are more likely to develop defective appestats than those that are breast-fed. |
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All the lions and lionesses here are of a hybrid stock and thus are prone to producing defective offspring, it is pointed out. |
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Will this bizarre heist sizzle like a bottle rocket or fizzle like a defective firecracker? |
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All three cars made it to a sideroad without further incident, and the defective driver came out to assess the damage. |
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The second exception to the general rule occurs when a party is at fault in employing wrong or defective procedures. |
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Use of defective tack is not a risk of horseback riding that an equine provider is unable to eliminate. |
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The fact that it doesn't even show up in the device manager makes me think it might be damaged or defective. |
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This meant that a milkman who was injured by a defective manhole cover could not sue the owner of the land over which the right of way passed. |
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Some 24 vehicles were found to have bald tyres while 12 had defective lights. |
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Some buses examined by inspectors in the last year have been found to have defective steering, faulty brakes or even bald tyres. |
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The patient said that as a young man he had used the Bates method for improving defective vision. |
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In Being and Time Heidegger says that being along is a deficient or defective mode of being. |
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Darwinian biology explained how humans evolved from other life forms, and Mendelian genetics showed how defective traits were inherited. |
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However, at later stages, the specification of the prosencephalon and the mesencephalon remains defective. |
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The defendants resold part of one shipment of lumber and later complained that the lumber was defective and refused to pay for it. |
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This finding implied that the mutants are defective in heme-oxygenase, an enzyme that converts heme into biliverdin. |
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A flawed acquisition strategy and a defective management approach exacerbated the cost misestimation. |
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We mutagenized a wild-type strain and sought animals that were defective in cultivation-temperature avoidance. |
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By comparison, the risk from defective, counterfeit or mislabeled drugs from Canada is presumed but unproved by any evidence. |
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So what is the hesitancy then for the modification of defective genes in germ cells or somatic cells? |
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Some were defective when they arrived in the theater and lacked enough spare parts to effect repairs. |
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The poor condition of that tiling and the defective mortar to the verge tiling generally warranted further investigation, in Mr Bruce's opinion. |
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On the laboratory's first day of operation, a defective aircraft engine was identified through spectrometric wear metal analysis. |
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In fact most people do not realise there are at least eight different classifications of colour defective vision plus individual variations. |
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The list of faults included defective tyres, faulty brakes and defective steering. |
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Black and white do not exist, they creep into the story due to the unpredictable magic of film processing or defective film stock. |
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The evidence at trial did not indicate to me that defective or substandard materials were used in the construction of this house. |
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The variety, character, and pungency of tone in the flue work, is as admirable as their reeds and swell organs are poor and defective. |
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This is running off the parapet above and is caused from defective rainwater disposal at second storey level to the external balcony. |
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Please provide us with a final account for work done adjusted to take account of defective and incomplete work. |
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Common causes of warping include faulty installation or defective manufacture of the siding. |
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The buses banned immediately were found to have defective brakes, tyres, air leaks, insecure doors and seats. |
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The officials were instructed to itemize the number of signatures from each county that are deemed defective for any of 10 reasons. |
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Besides consanguineous marriages, there are other reasons for a baby to be born with a defective heart. |
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On the interior of the church, all areas of defective plasterwork and cement based plaster have been hacked off. |
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Commenting on the lack of water in the downtown fire hydrants, Alfred said they were 50 years old and some were defective. |
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Granting that this plea of tender into court is defective, it would not render the petition insufficient to state a cause of action. |
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That was a claim by several steel dressers who were suffering from pneumoconiosis attributable to defective ventilation in a factory. |
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For the reasons given in respect of item 16 I am not satisfied that the failure to avoid ponding amounted to defective work. |
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Smaller warehouses and cotton gins have to ship defective bales to a warehouse or gin that has the necessary equipment. |
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There is some validity in their argument, because if our understanding is inherently imperfect, regulations are bound to be defective. |
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Weak or defective spaces in the organs or tissues are where a pathological condition is likely to begin. |
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I think I spent most of my childhood under the impression that I just wasn't trying hard enough, or that perhaps my vision was somehow defective. |
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Careless driving includes using a mobile phone while driving, driving without care or attention or with broken or defective lights. |
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During a three-hour check of 59 Hackney carriages and private hire vehicles they found eight had defective tyres, while one had a faulty exhaust. |
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My idea was to get a bunch of cheap wallets and fill my bag with junk, like defective cameras and broken portable CD players. |
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A genetic selection for mutants that activate this pathway uncovered a class of mutants defective in cell wall integrity. |
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A case study of cause-and-effect, it's also a yarn of dangerously defective brotherly love. |
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Responses to GIP have been shown to be defective in type 2 diabetic patients. |
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It may be, however, that the person purporting to grant the lease proves to have a defective title himself. |
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Scientists in Yorkshire have discovered a defective gene which they believe is a major cause of tunnel vision. |
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And a 1916 feature film even encouraged people to marry eugenically and kill their defective offspring. |
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If victimisation's grip over artists like him is moot, maybe its ability to regiment society evermore is defective as well. |
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The indictment was not duplicitous or in any way defective, but accurately encapsulated that allegation. |
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In addition, a defective epithelial layer can allow bacteria to gain entry into the human host. |
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Another defective specimen cause of erroneous diagnosis is that of extraneous tissue unappreciated as foreign to that sample. |
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If you are on the top floor, the source of the problem may be coming from a defective gutter or downpipe, or defective roof covering. |
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Summonses totalling R416000 have been served on drivers whose vehicles were found to have defects which included smooth tyres, defective brakes and faulty lights. |
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Our service and post-sales support is designed to replace faulty or defective products, and to provide training for the proper operation and configuration of network hardware. |
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I've heard stories flying around about paint cans, defective sprinkler systems, and a stash of fireworks in the back room of the comic-book store. |
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We reasoned that if programmed cell death influences organismal death, mutants defective in apoptosis should have abnormal, possibly extended, life spans. |
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Owners, architects, and contractors should specify and install products in compliance with this standard or risk claims of defective specifications of products. |
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His genetically defective double thumbs would give him away. |
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The commissioner also heard that on other occasions a Hunter's coach had been found with a defective tyre in Bridlington, and another had a defective speed limiter. |
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People who are obese, on corticosteroid therapy, or those with defective white blood cell function may be predisposed to furuncles and carbuncles. |
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For a long time we wanted to believe that here we were dealing with abnormal monsters, psychopaths, or mentally defective, even psychotic individuals. |
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Any vehicle, trailer or caravan with defective tyres is a potential death trap and we are determined to do all we can to remove them from the roads. |
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Like the readings which are defective in all examined copies but were apparently correct at one time, some of these variants may be attributed to type batter. |
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The plants had defective shoot apical meristems and grew slowly in vitro. |
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In fact, until recently, it has long been considered that the greenback dollar was a defective note, so simple in design that it was easy to fake. |
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Six drivers were prevented from travelling any further after their vehicles were found to have loose axle bolts, defective tyres and broken springs. |
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How can the story of a mentally defective kleptomaniac, a bookish nympho, a crippled FBI agent and a suicidal millionaire's son add up to anything but trouble? |
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Let us, through persuasion and education, seek to improve institutions we deem defective. |
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The profiles of the different defective oils are quite different with noticeably increased amounts of less volatile compounds in winey-vinegary, rancid, and fausty sensory defects. |
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Often they were offloading defective goods they could not sell at a shop. |
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It is understood that the sellers liability in respect of defective or otherwise unmerchantable goods shall not at any time extend beyond the actual price paid for such goods. |
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Hundreds of injuries, and some deaths, were linked to such devices as defective heart valves, faulty pacemakers, and substandard intrauterine devices. |
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The County Council on the other hand contended that the offences were continuing offences, continuing so long as the defective reinstatement remained unrectified. |
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Anyone who takes pot shots at a lovely wading bird is a hopeless defective, in my view, an evolutionary mistake. |
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It is a misfortune that the text of the history of Ammianus Marcellinus, which introduces this episode, is defective, and that only allusive back references survive. |
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He is of the opinion that the defective brake drums and maladjustment of the steering tillers certainly would not have enhanced the handling of the vehicle. |
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In the Queenstown area, drivers were caught for overloading taxis and displaying incorrect number plates or defective wheels, brakes and steering wheels. |
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Seven years ago, a chevy Cobalt with a defective ignition switch killed two teenage girls. |
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The legislation, according to its critics, would have provided legal loopholes for those responsible for defective products, faulty construction and even criminal acts. |
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He guessed that the original cutting stylus was defective and so he tried a custom-made reproducing stylus, instead of the usual conical or elliptical styli. |
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In The conjuring, the Warrens brush off alleged hauntings as the result of drafts or defective pipes. |
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The finding may also mean that, in severe cases, it may be more appropriate to remove the defective adrenals and administer cortisol and other adrenal hormones artificially. |
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Apple packing houses currently rely on digital camera imagery to sort apples by surface appearance only, flagging those that are visibly defective or the wrong size or color. |
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The team can fit grab-rails on staircases and in doorways, fix defective carpets or floor coverings, remove trailing wires and generally reduce trip hazards. |
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By either estimate, the defective switch cost Amy Rademaker and at least a dozen other people their lives. |
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Seattle was faster, stronger, hungrier, and more prepared, and Manning seemed like a wizard with a defective wand. |
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The crude birth rate may also be adjusted for age-sex composition by the indirect method when age-specific birth rates for the particular population are lacking or defective. |
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Besides, the cone was probably not exposed to pollen of other lacebarks and the seeds were probably empty or defective, as pines don't do self-pollination well. |
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Owners frequently ask whether their boat warranty entitles them to a complete replacement or refund of the purchase price if the vessel proves defective. |
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This phenotype may be the result of defective interaxon communication that obstructs axon extension or fasciculation in the longitudinal pathways. |
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Many modern editions, including the Oxford, take the view that the novel in part derives from the play, and use it to emend the defective quarto text. |
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The trial was investigating a treatment for a genetic liver condition, where a gene for a liver enzyme, ornithine trans-carbamylase, is either missing or defective. |
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In the 6 to 1 ruling, the court rejected the mother's charge that the semi-automatic handgun was defective because it lacked a lock to make it childproof. |
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The verb can is defective in most English dialects, as it lacks an infinitive. |
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The thrombocytes were increased in the peripheral blood smear and defective thrombocytes were present. |
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The automaker is replacing the engines because of a defective timing chain and guide, which can cause a clattering noise. |
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We now understand that ADPKD and a number of other hereditary kidney diseases are all due to defective cilial proteins. |
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While Brazil enacted a consumer rights code in 1990, none of its 119 articles mentions a right to a refund, even if the item is defective. |
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Along with another cousin, Lillian Gregg, Elfrida set up a kindergarten for children considered uneducable and mentally defective. |
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Poorly fitted, unprotective, defective, and worn out shoes can play a major role in developing a running injury. |
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Many of the companies that sold the defective units, like Trane and Sears, are replacing them, a CPSC report said. |
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Protein misfolding, congophilia, oligomerization, and defective amyloid processing in preeclampsia. |
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The specific defective gene that causes CF is the cystic fibrosis transmembrane conductance regulator gene. |
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Cancer grows anyway, since the mitochondria and cytoplasm are still defective in the resulting clone. |
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Two pathophysiologic mechanisms contribute to hypoglycemia in diabetes, namely defective glucose counterregulation and hypoglycemia unawareness. |
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The Germans knew nothing of our defective staff work or the risks we had run. |
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He knew why the building was so damp. Its damp courses were defective and it was built on top of the tank stream. |
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A rice heterochronic mutant, moril, is defective in the juvenile-adult phase change. |
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The report for 1909 showed that 42 per cent. of the children's months were defective dentitionally. |
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Ow! These things are defective. Pipsqueak, be a doll, I need a new pair, pronto! |
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Nor will polished Amber although it send forth a gross and corporal exhalement, be found a long time defective upon the exactest scales. |
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I'll see your defective gallbladder and raise you one heart murmur and a kidney stone. |
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The initial survey for the line was carried out by William James and, being done surreptitiously or by trespass, was defective. |
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This tree was defective in both, yielding nothing but an empty shade to the mishoping traveller. |
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The procedure is used when a woman with genetically defective mitochondria wishes to procreate and produce offspring with healthy mitochondria. |
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Colonel Yolland made an inspection in August 1866, but this time there were many deficiencies, including defective track. |
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As well as creating cells, bone marrow is also one of the major sites where defective or aged red blood cells are destroyed. |
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His anatomic knowledge of humans was defective because it was based on dissection of animals, mainly apes, sheep, goats and pigs. |
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Modal verbs are defective insofar as they cannot be inflected, nor do they appear as gerunds, infinitives, or participles. |
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But it observed that this shows that the Anglicans themselves perceived that the first form was defective and inadequate. |
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It was conceded that the defective wheel could have been discovered upon inspection. |
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However, compensation for defective but not unsafe products is typically available only through contractual actions through the law of warranty. |
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Injuries resulting from defective products were normally claimed on the basis of a contract of sale between the seller and the consumer. |
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Wrought iron may be welded in the same manner as mild steel, but the presence of oxide or inclusions will give defective results. |
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In 1905, a passenger train was derailed at Murthwaite due to a combination of a defective locomotive and defective track. |
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The goal of this paper is to defend the actualist desire-satisfaction theory against the problem of defective desires. |
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The truck violations included worn tires, worn brakes, improper loads and defective air brake lines. |
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The affected 1998 to 2006 Mercedes vehicles have defective catalytic converters or defective air pumps. |
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For example, a defective Hellfire or Stinger missile that can't be jettisoned could go ka-boom. |
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A third alternative for purchasers of defective cars is to turn to the state lemon law. |
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Their study, published online January 12, 2014 in Nature, used stem cells to correct a defective ring chromosome with a normal chromosome. |
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Encrustations at defective joints had temporarily re-sealed defects in the lateral causing pressure testing to record a false-positive result. |
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Two other patients had multiple myeloma, which has a well-known association with defective humoral immunity. |
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Vitamin A deficiency during pre-eruptive stages of tooth development leads to enamel hypoplasia and defective dentin formation. |
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Case with symmetrical congenital notches in the Outer part of each lid and defective development of the malar bones. |
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LeVier and her colleagues found that Brucella abortus with defective bacA enters mouse cells but can't create a chronic infection. |
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Afzelius had noticed that the men's sperm had defective flagella, the whiplike tails that are essentially modified cilia. |
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Mitochondria are found in nearly every cell of the body, and defective mitochondria leave the body with insufficient energy to function. |
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Under the new rules, IVF clinics will be able to replace a baby's defective mitochondrial DNA with healthy DNA from a female donor's egg. |
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In pediatric thalassemic patients, iron overload is responsible for delayed bone age and defective mineralization. |
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The catalogue describes this manuscript as having 105 leaves, but the modern foliation is defective, for following fol. |
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Fortunately, reflectors can be polished or replaced if found defective, thereby considerably improving the efficiency of headlighting on older cars. |
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Lander, and Albert de la Chapelle of the University of Helsinki assumed that the defective DTD gene most likely arose from one person in that group. |
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Strigolactones are produced by the non-mycorrhizal plant Arabidopsis thaliana, and plant mutants defective for strigolactone production have not yet been obtained. |
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When a patient has such a mutation, he or she manufactures a defective version of the protein homogentisate dioxygenase and, thus, suffers from alkaptonuria. |
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In an inherited condition called achondroplasia, defective bone formation results in abnormally short and thickened pedicles that reduce the diameter of the spinal canal. |
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With a defective gene, a cell makes little or no ADA enzyme. |
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Development of defective and persistent Sendai virus vector. |
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Its fiery stripes resemble the defective pigmentation of someone's skin, but you still feel invited by the rondure of the apple to stroke it, to clasp it. |
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However, thymine dimer repair was markedly reduced in mice lacking the VDR, indicating that these mice have defective DNA repair mechanisms in UV-induced damage. |
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When collagen is missing or defective, body parts where connective tissue is most important, such as skin, joints, and blood vessels, behave abnormally. |
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Bell case that upheld the Virginia Sterilization Act of 1924 and the forced sterilization of Carrie Buck who was claimed to be mentally defective. |
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Its declension is defective, in the sense that it lacks a reflexive form. |
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A combination of non-teratologic doses of the two drugs often increased the incidence of embryos with defective neural tube closure and somite formation. |
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Results indicate that occupational exposures to relatively low levels of benzene were associated with increased incidence of chromosomally defective sperm. |
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Investigators determined that an oil leak, caused by a defective oil supply pipe, led to an engine fire and subsequent uncontained engine failure. |
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