How to use Defective in a sentence

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Sentence Examples Defective mitochondria can slow down or prevent the growth of a fertilised egg, preventing conception. Defective mDNA from a mother's egg can be replaced with healthy mDNA from a donor. Defective MDNA from an egg can be replaced with healthy MDNA from a donor egg to prevent harmful mutations being passed on. Defective connective tissue leads to fragile capillaries, resulting in abnormal bleeding. Defective cholesterol biosynthesis in Smith-Lemli-Opitz syndrome. Defective types of psychoses are the most interesting kinds, like the maniacs, the melancholiacs, the phobiacs, the paranoiacs, the neurasthenics, the hysterical, etc. In fact most people do not realise there are at least eight different classifications of colour defective vision plus individual variations. The list of faults included defective tyres, faulty brakes and defective steering. This defective recovery of DNA replication suggests an inability to coordinate lesion bypass or to initiate new replicons. This could involve the expression in a yeast mutant, which is defective for an analogous transport system. Once the buyer has shown goods to be defective, strict liability arises for their consequences. Responses to GIP have been shown to be defective in type 2 diabetic patients. A further 16 charges, relating to driving with a defective speed limiter, were found proven. It is also thought by some authorities that bottle-fed babies are more likely to develop defective appestats than those that are breast-fed. All the lions and lionesses here are of a hybrid stock and thus are prone to producing defective offspring, it is pointed out. Will this bizarre heist sizzle like a bottle rocket or fizzle like a defective firecracker? The indictment was not duplicitous or in any way defective, but accurately encapsulated that allegation. All three cars made it to a sideroad without further incident, and the defective driver came out to assess the damage. The second exception to the general rule occurs when a party is at fault in employing wrong or defective procedures. Use of defective tack is not a risk of horseback riding that an equine provider is unable to eliminate. Show More Sentences If victimisation's grip over artists like him is moot, maybe its ability to regiment society evermore is defective as well. The fact that it doesn't even show up in the device manager makes me think it might be damaged or defective. This meant that a milkman who was injured by a defective manhole cover could not sue the owner of the land over which the right of way passed. Some 24 vehicles were found to have bald tyres while 12 had defective lights. Some buses examined by inspectors in the last year have been found to have defective steering, faulty brakes or even bald tyres. And a 1916 feature film even encouraged people to marry eugenically and kill their defective offspring. The horse escaped from its stable during the night into the field and thence onto the railway line via a defective fence. In accordance with the terms of this limited warranty, the company, at its expense shall repair or replace the product which is proven defective. Scientists in Yorkshire have discovered a defective gene which they believe is a major cause of tunnel vision. The patient said that as a young man he had used the Bates method for improving defective vision. In Being and Time Heidegger says that being along is a deficient or defective mode of being. Darwinian biology explained how humans evolved from other life forms, and Mendelian genetics showed how defective traits were inherited. However, at later stages, the specification of the prosencephalon and the mesencephalon remains defective. If you are on the top floor, the source of the problem may be coming from a defective gutter or downpipe, or defective roof covering. The defendants resold part of one shipment of lumber and later complained that the lumber was defective and refused to pay for it. This finding implied that the mutants are defective in heme-oxygenase, an enzyme that converts heme into biliverdin. But it has been proved that actually defective vehicles have contributed to accidents on Zambian roads. A flawed acquisition strategy and a defective management approach exacerbated the cost misestimation. In short, the vertebrate eye is a masterpiece not of design, but of jury-rigged compensations for a fundamentally defective architecture. Once the grafts had matured they were used to reconstruct defective windpipes in seven foetal lambs. Show More Sentences We mutagenized a wild-type strain and sought animals that were defective in cultivation-temperature avoidance. Since unmodified Ebola enters through, and attacks, the lungs, defective lung cells could benefit most from therapy based on this discovery. By comparison, the risk from defective, counterfeit or mislabeled drugs from Canada is presumed but unproved by any evidence. So what is the hesitancy then for the modification of defective genes in germ cells or somatic cells? It may be, however, that the person purporting to grant the lease proves to have a defective title himself. Some were defective when they arrived in the theater and lacked enough spare parts to effect repairs. The poor condition of that tiling and the defective mortar to the verge tiling generally warranted further investigation, in Mr Bruce's opinion. On the laboratory's first day of operation, a defective aircraft engine was identified through spectrometric wear metal analysis. A case study of cause-and-effect, it's also a yarn of dangerously defective brotherly love. Black and white do not exist, they creep into the story due to the unpredictable magic of film processing or defective film stock. If there is a bad set of specifications and a bad set of materials no good workman can fix the problem, because it is intrinsically defective. Vehicles with worn or defective shock absorbers are less stable and more liable to go out of control. The evidence at trial did not indicate to me that defective or substandard materials were used in the construction of this house. The variety, character, and pungency of tone in the flue work, is as admirable as their reeds and swell organs are poor and defective. This is running off the parapet above and is caused from defective rainwater disposal at second storey level to the external balcony. Finally, all the Ames test strains have defective polysaccharide outer coats, to make them more permeable to the test chemicals. Please provide us with a final account for work done adjusted to take account of defective and incomplete work. Common causes of warping include faulty installation or defective manufacture of the siding. The buses banned immediately were found to have defective brakes, tyres, air leaks, insecure doors and seats. The officials were instructed to itemize the number of signatures from each county that are deemed defective for any of 10 reasons. Show More Sentences Besides consanguineous marriages, there are other reasons for a baby to be born with a defective heart. On the interior of the church, all areas of defective plasterwork and cement based plaster have been hacked off. Commenting on the lack of water in the downtown fire hydrants, Alfred said they were 50 years old and some were defective. Granting that this plea of tender into court is defective, it would not render the petition insufficient to state a cause of action. That was a claim by several steel dressers who were suffering from pneumoconiosis attributable to defective ventilation in a factory. For the reasons given in respect of item 16 I am not satisfied that the failure to avoid ponding amounted to defective work. Smaller warehouses and cotton gins have to ship defective bales to a warehouse or gin that has the necessary equipment. There is some validity in their argument, because if our understanding is inherently imperfect, regulations are bound to be defective. Weak or defective spaces in the organs or tissues are where a pathological condition is likely to begin. I think I spent most of my childhood under the impression that I just wasn't trying hard enough, or that perhaps my vision was somehow defective. Careless driving includes using a mobile phone while driving, driving without care or attention or with broken or defective lights. During a three-hour check of 59 Hackney carriages and private hire vehicles they found eight had defective tyres, while one had a faulty exhaust. My idea was to get a bunch of cheap wallets and fill my bag with junk, like defective cameras and broken portable CD players. Mutants that grew on these plates were judged to be defective in glucose metabolism and were not studied further. A genetic selection for mutants that activate this pathway uncovered a class of mutants defective in cell wall integrity. Another defective specimen cause of erroneous diagnosis is that of extraneous tissue unappreciated as foreign to that sample. In addition, a defective epithelial layer can allow bacteria to gain entry into the human host. The second major category of error is that of defective identification of patient, tissue, or laterality. Often they were offloading defective goods they could not sell at a shop. In the Queenstown area, drivers were caught for overloading taxis and displaying incorrect number plates or defective wheels, brakes and steering wheels. Show More Sentences It is a misfortune that the text of the history of Ammianus Marcellinus, which introduces this episode, is defective, and that only allusive back references survive. We reasoned that if programmed cell death influences organismal death, mutants defective in apoptosis should have abnormal, possibly extended, life spans. The trial was investigating a treatment for a genetic liver condition, where a gene for a liver enzyme, ornithine trans-carbamylase, is either missing or defective. How can the story of a mentally defective kleptomaniac, a bookish nympho, a crippled FBI agent and a suicidal millionaire's son add up to anything but trouble? The team can fit grab-rails on staircases and in doorways, fix defective carpets or floor coverings, remove trailing wires and generally reduce trip hazards. In the 6 to 1 ruling, the court rejected the mother's charge that the semi-automatic handgun was defective because it lacked a lock to make it childproof. The County Council on the other hand contended that the offences were continuing offences, continuing so long as the defective reinstatement remained unrectified. By either estimate, the defective switch cost Amy Rademaker and at least a dozen other people their lives. He guessed that the original cutting stylus was defective and so he tried a custom-made reproducing stylus, instead of the usual conical or elliptical styli. This phenotype may be the result of defective interaxon communication that obstructs axon extension or fasciculation in the longitudinal pathways. The plants had defective shoot apical meristems and grew slowly in vitro. Anyone who takes pot shots at a lovely wading bird is a hopeless defective, in my view, an evolutionary mistake. Owners, architects, and contractors should specify and install products in compliance with this standard or risk claims of defective specifications of products. It is understood that the sellers liability in respect of defective or otherwise unmerchantable goods shall not at any time extend beyond the actual price paid for such goods. The commissioner also heard that on other occasions a Hunter's coach had been found with a defective tyre in Bridlington, and another had a defective speed limiter. Let us, through persuasion and education, seek to improve institutions we deem defective. In The conjuring, the Warrens brush off alleged hauntings as the result of drafts or defective pipes. For a long time we wanted to believe that here we were dealing with abnormal monsters, psychopaths, or mentally defective, even psychotic individuals. The profiles of the different defective oils are quite different with noticeably increased amounts of less volatile compounds in winey-vinegary, rancid, and fausty sensory defects. The finding may also mean that, in severe cases, it may be more appropriate to remove the defective adrenals and administer cortisol and other adrenal hormones artificially. Show More Sentences The crude birth rate may also be adjusted for age-sex composition by the indirect method when age-specific birth rates for the particular population are lacking or defective. Like the readings which are defective in all examined copies but were apparently correct at one time, some of these variants may be attributed to type batter. People who are obese, on corticosteroid therapy, or those with defective white blood cell function may be predisposed to furuncles and carbuncles. His genetically defective double thumbs would give him away. Any vehicle, trailer or caravan with defective tyres is a potential death trap and we are determined to do all we can to remove them from the roads. Summonses totalling R416000 have been served on drivers whose vehicles were found to have defects which included smooth tyres, defective brakes and faulty lights. Our service and post-sales support is designed to replace faulty or defective products, and to provide training for the proper operation and configuration of network hardware. He is of the opinion that the defective brake drums and maladjustment of the steering tillers certainly would not have enhanced the handling of the vehicle. Hundreds of injuries, and some deaths, were linked to such devices as defective heart valves, faulty pacemakers, and substandard intrauterine devices. In fact, until recently, it has long been considered that the greenback dollar was a defective note, so simple in design that it was easy to fake. Many modern editions, including the Oxford, take the view that the novel in part derives from the play, and use it to emend the defective quarto text. The legislation, according to its critics, would have provided legal loopholes for those responsible for defective products, faulty construction and even criminal acts. Apple packing houses currently rely on digital camera imagery to sort apples by surface appearance only, flagging those that are visibly defective or the wrong size or color. I've heard stories flying around about paint cans, defective sprinkler systems, and a stash of fireworks in the back room of the comic-book store. Six drivers were prevented from travelling any further after their vehicles were found to have loose axle bolts, defective tyres and broken springs. Seattle was faster, stronger, hungrier, and more prepared, and Manning seemed like a wizard with a defective wand. Seven years ago, a chevy Cobalt with a defective ignition switch killed two teenage girls. Owners frequently ask whether their boat warranty entitles them to a complete replacement or refund of the purchase price if the vessel proves defective. Besides, the cone was probably not exposed to pollen of other lacebarks and the seeds were probably empty or defective, as pines don't do self-pollination well. Mitochondria are found in nearly every cell of the body, and defective mitochondria leave the body with insufficient energy to function. Show More Sentences He knew why the building was so damp. Its damp courses were defective and it was built on top of the tank stream. The verb can is defective in most English dialects, as it lacks an infinitive. The report for 1909 showed that 42 per cent. of the children's months were defective dentitionally. Ow! These things are defective. Pipsqueak, be a doll, I need a new pair, pronto! Nor will polished Amber although it send forth a gross and corporal exhalement, be found a long time defective upon the exactest scales. I'll see your defective gallbladder and raise you one heart murmur and a kidney stone. The initial survey for the line was carried out by William James and, being done surreptitiously or by trespass, was defective. This tree was defective in both, yielding nothing but an empty shade to the mishoping traveller. The Germans knew nothing of our defective staff work or the risks we had run. The procedure is used when a woman with genetically defective mitochondria wishes to procreate and produce offspring with healthy mitochondria. Colonel Yolland made an inspection in August 1866, but this time there were many deficiencies, including defective track. As well as creating cells, bone marrow is also one of the major sites where defective or aged red blood cells are destroyed. His anatomic knowledge of humans was defective because it was based on dissection of animals, mainly apes, sheep, goats and pigs. Modal verbs are defective insofar as they cannot be inflected, nor do they appear as gerunds, infinitives, or participles. But it observed that this shows that the Anglicans themselves perceived that the first form was defective and inadequate. It was conceded that the defective wheel could have been discovered upon inspection. However, compensation for defective but not unsafe products is typically available only through contractual actions through the law of warranty. Injuries resulting from defective products were normally claimed on the basis of a contract of sale between the seller and the consumer. Wrought iron may be welded in the same manner as mild steel, but the presence of oxide or inclusions will give defective results. In 1905, a passenger train was derailed at Murthwaite due to a combination of a defective locomotive and defective track. Show More Sentences The goal of this paper is to defend the actualist desire-satisfaction theory against the problem of defective desires. The truck violations included worn tires, worn brakes, improper loads and defective air brake lines. The affected 1998 to 2006 Mercedes vehicles have defective catalytic converters or defective air pumps. For example, a defective Hellfire or Stinger missile that can't be jettisoned could go ka-boom. A third alternative for purchasers of defective cars is to turn to the state lemon law. Their study, published online January 12, 2014 in Nature, used stem cells to correct a defective ring chromosome with a normal chromosome. Case with symmetrical congenital notches in the Outer part of each lid and defective development of the malar bones. LeVier and her colleagues found that Brucella abortus with defective bacA enters mouse cells but can't create a chronic infection. Under the new rules, IVF clinics will be able to replace a baby's defective mitochondrial DNA with healthy DNA from a female donor's egg. In pediatric thalassemic patients, iron overload is responsible for delayed bone age and defective mineralization. A rice heterochronic mutant, moril, is defective in the juvenile-adult phase change. The thrombocytes were increased in the peripheral blood smear and defective thrombocytes were present. The automaker is replacing the engines because of a defective timing chain and guide, which can cause a clattering noise. We now understand that ADPKD and a number of other hereditary kidney diseases are all due to defective cilial proteins. While Brazil enacted a consumer rights code in 1990, none of its 119 articles mentions a right to a refund, even if the item is defective. Along with another cousin, Lillian Gregg, Elfrida set up a kindergarten for children considered uneducable and mentally defective. Poorly fitted, unprotective, defective, and worn out shoes can play a major role in developing a running injury. Many of the companies that sold the defective units, like Trane and Sears, are replacing them, a CPSC report said. Protein misfolding, congophilia, oligomerization, and defective amyloid processing in preeclampsia. The specific defective gene that causes CF is the cystic fibrosis transmembrane conductance regulator gene. Show More Sentences Cancer grows anyway, since the mitochondria and cytoplasm are still defective in the resulting clone. Two pathophysiologic mechanisms contribute to hypoglycemia in diabetes, namely defective glucose counterregulation and hypoglycemia unawareness. Encrustations at defective joints had temporarily re-sealed defects in the lateral causing pressure testing to record a false-positive result. Two other patients had multiple myeloma, which has a well-known association with defective humoral immunity. Vitamin A deficiency during pre-eruptive stages of tooth development leads to enamel hypoplasia and defective dentin formation. Afzelius had noticed that the men's sperm had defective flagella, the whiplike tails that are essentially modified cilia. The catalogue describes this manuscript as having 105 leaves, but the modern foliation is defective, for following fol. When a patient has such a mutation, he or she manufactures a defective version of the protein homogentisate dioxygenase and, thus, suffers from alkaptonuria. Lander, and Albert de la Chapelle of the University of Helsinki assumed that the defective DTD gene most likely arose from one person in that group. In an inherited condition called achondroplasia, defective bone formation results in abnormally short and thickened pedicles that reduce the diameter of the spinal canal. When collagen is missing or defective, body parts where connective tissue is most important, such as skin, joints, and blood vessels, behave abnormally. Results indicate that occupational exposures to relatively low levels of benzene were associated with increased incidence of chromosomally defective sperm. However, thymine dimer repair was markedly reduced in mice lacking the VDR, indicating that these mice have defective DNA repair mechanisms in UV-induced damage. A combination of non-teratologic doses of the two drugs often increased the incidence of embryos with defective neural tube closure and somite formation. With a defective gene, a cell makes little or no ADA enzyme. Development of defective and persistent Sendai virus vector. Its fiery stripes resemble the defective pigmentation of someone's skin, but you still feel invited by the rondure of the apple to stroke it, to clasp it. Bell case that upheld the Virginia Sterilization Act of 1924 and the forced sterilization of Carrie Buck who was claimed to be mentally defective. Its declension is defective, in the sense that it lacks a reflexive form. Strigolactones are produced by the non-mycorrhizal plant Arabidopsis thaliana, and plant mutants defective for strigolactone production have not yet been obtained. Show More Sentences Investigators determined that an oil leak, caused by a defective oil supply pipe, led to an engine fire and subsequent uncontained engine failure. Fortunately, reflectors can be polished or replaced if found defective, thereby considerably improving the efficiency of headlighting on older cars. Examples from Classical Literature Defective calcification of the forming bone is one of the principal characteristics of rachitis. Defective metre and sense, owing to the loss of a hemistich, but the sense is complete. This convolution is comparatively defective in animals generally, but more developed in birds of superior vocal powers. The first type of family is often termed aristogenic and the second or defective type, cacogenic. In cases of anasarca, the skin, kidneys, and bowels are very defective in their operation. And they that think it culpably defective in phrase, aptness, or elegancy of style. When he emerged, it was with the avowed belief that the armature had been defective when received. Brunonian System, a system which regards and treats diseases as due to defective or excessive excitation, as sthenic or asthenic. An overflow is provided, discharging into the open air to allow the water to escape should the ball valve become defective. Short of cases of certifiable insanity there are a number of prisoners who are mentally defective. It is due to defective development of the embryo and is as a rule found in association with cleft palate. Another frequent abnormality is cleft palate, a fissure in the palate, due to defective development. Jimmy has so long lived away from Brownsville that his memory is defective. The corner of the 'W' instead of being clear and distinct, is blunt and defective. It is obvious that a defective vacuum may or may not prevent an engine from starting, according to the degree of defectiveness. Of this the English version is as defective as our school-book account of the Revolution. So far as we fail to do this our view of divine truth is defective and disproportioned. If he comprehends only slowly or fails to understand, he is a dullard or a defective. The courts of equity also will interfere in some cases of defective execution in order to carry out the intentions of the settlor. In many cases which have been described as primary atrophy the histological investigation of the stomach has been very defective. Show More Sentences Since then Dr. Decroly, who specialises on defective children in Belgium, has tried our methods, and verified our conclusions. Asthenopia, which occurs in children in connection with hypermetropia, is nearly always accompanied by defective vision. The student has already seen that Maori is defective in particles of illation, comparison, and copulation. Approximately one-half of the incense cedar trees, as they stand in the woods, are defective. If it is defective, the defect all comes from some want of strenuousness as you went along. Should it not be considered a mark of defective cultivation to be insensitive to color? His telautograph worked on what is known as the step-by-step principle, and was defective in that its speed was very limited. But it is a most awkward, operose, and defective piece of machinery, quite unworthy of being presented to my readers. In times of overstress and strain, the defective organ or organs will manifest their weakness. I thin the fruit while on the trees by picking off the wormy and defective ones. In proliferous flowers the pistil is often completely defective, its place being occupied by the adventitious bud or axis. It started because of that defective spark-plug in the engine of the roadster. She is also defective in her knowledge of hebridean geography. As they learned later a defective rail had caused the smash-up. You have permitted sentiment to influence you, thus demonstrating that you are a defective. From cold, calculating, highly intelligent perversity it had deteriorated into the indiscriminating, dangerous menace of the mentally defective. The automaker is recalling the vehicles due to a defective pawl spring tab within the door-latch assembly. A recombinant influenza A virus expressing an RNA-binding defective NS1 protein induces high levels of beta interferon and is attenuated in mice. Tenders are invited for Electrical work of replacement of old defective submersible pump setoff NIE Guest House Campus New Delhi. The postal service on the shore of Greenland is very defective. Show More Sentences The sewerage is generally good, but defective in some places. But his learning had grown rusty with disuse, and his vocabulary was defective and capricious. A defective governor may also cause the compressor to run slow. The result is an accumulation of defective daughter cells with the wrong number of chromosomes and therefore the wrong number of genes. The automaker is recalling the vehicles to fix a defective front shock absorber piston rod. Adenoids and defective vision are preventable, but not contagious. One of the most common forms of defective vision is astigmatism. If I find it defective, I should serve it by purging it of its defects. Meanwhile, the yardstick to be used by the other 48 remains as defective as ever. This is important in avoiding potentially dangerous entrapment from defective covers. And what if some of these parts happen to be malformed or defective? The teeth are defective, and mastication and insalivation are neglected. The defective points of Martha's character seem to have been two. Any of these elements lacking, and the life is wanting, defective, impure. And for the unrestraint of her manner defective training in early girlhood would account. Of what use is fortune or talent to a cold and defective nature? It was a defective barometer, and had no hand but the stationary brass pointer, but I did not know that until afterward. Now imagine that the original factory workers, before fleering for their lives, secretly reprogram one of the machines to make a defective component. President Reagan thought the treaty was irremediably defective. One reason for doubt is that the Republic characterises the Laconian as one of the four defective constitutions, a city loving honour and victory rather than wisdom. Show More Sentences After said defective peery fell off she was able to carry on with her evening's fun and even managed to sink a few sherbets with her mates before she passed out. Hann discovered defective threads on M-99 canopy jettison initiators prior to issue from the Davis-Monthan AFB Munitions Stockpile Surveillance section. The learning of this people is very defective, consisting only in morality, history, poetry, and mathematics, wherein they must be allowed to excel. Failure to file a lawsuit within the applicable state's statute of limitations will, in most cases, prevent recovery for claims related to this defective medical device. Find more words! 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