Additional studies suggested a mechanism of action resembling that of the antimitotic drug vincristine. |
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Targeted compounds were evaluated for antimitotic microtubule destabilizing activity using a phenotypic sea urchin embryo assay. |
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Taxanes are potent antimitotic agents that have demonstrated efficacy in a wide range of malignancies. |
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It was found that phenstatin ring A modifications yielded antimitotic compounds. |
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Mitotic drug target and the development of novel antimitotic anticancer drugs. |
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For example, a trial on a new antimitotic agent on one hand, and collecting a few extra mls of blood when blood is sampled for the purpose of making a diagnosis on the other hand, should be dealt with differently. |
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Synthesis of a new 4-aza2,3-didehydropodophyllotoxin analogues as potent cytotoxic and antimitotic agents. |
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In contrast, the novel heterocycle annulated seven membered B-ring variants 15 and 16 proved to be highly potent tubulin-inhibitory, antimitotic agents. |
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