By recognizing and attaching to these proteins, monoclonal antibodies can interfere with normal or abnormal cellular responses. |
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In addition, protein metabolism becomes chaotic and disorderly, leading to mutant antibodies becoming auto-antibodies. |
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Several methods are available to prevent the formation of preformed reactive antibodies to HLA antigens. |
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Human science employs somewhat similar procedures to produce what are called antitoxins, protein antibodies, to certain microorganisms. |
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The system, in the form of antibodies, attacks and damages the nerve signal reception areas in the body. |
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With the help of specially designed monoclonal antibodies, they collected devil's coach-horse beetles and analysed their guts. |
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Proteins have high affinities for their substrates or co-factors or prosthetic groups or receptors or antibodies raised against them. |
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Early-stage dementia or Alzheimer's disease may be associated with gluten antibodies. |
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In contrast, more cross-reactive antibodies are believed to be more flexible and involve less specific contacts. |
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Furthermore, polyclonal antibodies were used to assess quantitative and qualitative changes of the enzyme. |
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Preliminary experiments confirmed that these antibodies only cross-reacted with proteins of an expected size in E. nindensis. |
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The new diagnostic kits can detect the virus or antibodies for the virus in nasal or throat secretions and serum. |
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She said the life-threatening condition developed when her own antibodies attacked the baby's blood cells. |
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In the case of symmetrical lupoid onychodystrophy, Greyhounds form antibodies against their toe nails, and reject them. |
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These antibodies are believed to be the cause of the symptoms of systemic lupus, especially kidney disease. |
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Giving methotrexate concurrently, however, suppressed tachyphylaxis, probably by preventing the production of human antichimeric antibodies. |
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Cells were then fixed, rinsed, and labeled with fluorescently tagged secondary antibodies as described above. |
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Lysis is caused by enzymes known as lytic enzymes that are secreted by the antibodies. |
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The disease may no longer be common, so the production of antibodies or immunogenicity, rather than protection from disease, has to be assessed. |
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Cells were then permeablized with saponin and incubated with fluorescent-labeled antibodies, and four-color flow cytometry was performed. |
|
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A protein that cross-reacts with antibodies to actinin has been identified. |
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The diagnosis is confirmed by the tensilon test, electromyographic studies and the finding of elevated acetylcholine receptor antibodies. |
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When a test strip is dipped in yam sap, the sap will move along the strip, binding with antibodies that react with viruses. |
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Vaccines can stimulate the immune system to produce antibodies or specialized cells or both to stop invading viruses. |
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The selected cell is then fused with a neoplastic plasma cell that also has a natural propensity to make antibodies. |
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Their blood serum was tested for traces of antibodies against the influenza virus. |
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Monoclonal antibodies can also be produced by fusing a single plasma cell with an immortal myeloma cell line in the laboratory. |
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Processed plasma is also used to help produce stronger antibodies against diseases like tetanus, hepatitis, chickenpox and rabies. |
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In each later pregnancy, maternal Rh antibodies can cross the placenta and reach the fetus. |
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When we laugh, T cells, natural killer cells and cells that produce antibodies increase in number. |
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Thyroid antibodies were measured by an immunoradiographic procedure using thyroglobulin and purified thyroid peroxidase in 11 subjects. |
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Once the vaccine is injected into a person, the immune system reacts by producing antibodies programmed to attack the dead virus. |
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The proteins were detected by Western blots using antibodies specific for these proteins and three independent blots were analyzed. |
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At her next pregnancy the mother will then pass those antibodies against Rh-positive blood to the fetus. |
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At baseline, serum ferritin and antithyroid peroxidase antibodies were measured and a thyrotrophin releasing hormone test was performed. |
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But on a sadder note, I think my lips have developed antibodies to the tingly sensation. |
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A mare has only a limited supply of colostrum, which contains antibodies essential for the foal. |
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In endemic areas such as Africa, Asia, and South America there is a relatively high seroprevalence of antibodies to the organism. |
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Furthermore, antibodies to the region II domain of the protein are commonly detected in sera from individuals in endemic populations. |
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Earlier studies found that pregnant pigs vaccinated against bacterial intimin developed antibodies against it in their sera and colostrum. |
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Fucose was complexed with bovine serum albumin to raise antibodies against fucose. |
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It takes time for antibodies to develop, so having the test too early can lead to false negative results. |
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Capture antibodies that revealed binding to non-cognate antigens were removed or replaced with suitable alternatives. |
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For sure, they contain antibodies or a form of a micro-organism that won't cause an infection, but will cause our bodies to make antibodies. |
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Males responded to vaccination with diphtheria and tetanus toxoids by producing specific antibodies to both antigens. |
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The passive transmission of various antibodies from intravenous immunoglobulin has been reported. |
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Most of these proteins which contain peptide repeats are also immunogenic and the host produces significant amount of antibodies against these. |
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For immunoblots, proteins were transferred electrophoretically to nitrocellulose and resulting replicas were probed with antibodies. |
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Three rats were trapped in Kumarakom, a famous tourist spot in the district, and two were positive for leptospiral antibodies. |
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Fucose was ligated to bovine serum albumin and antibodies were raised against the conjugate. |
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We now know that these particular antibodies are rather weakly binding and only poorly specific. |
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Transverse taproot sections were treated with antibodies raised against the 23 kDa protein. |
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The filter is then probed with antibodies raised against a particular protein. |
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Secondary antibodies, dilutions, and mounting conditions were as described above. |
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These soluble molecules in the blood are usually glycoproteins detected by monoclonal antibodies. |
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Traditionally, most methods have used monoclonal antibodies and immunohistochemistry to identify tumour marker proteins. |
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Human leukocytes are identified by monoclonal antibodies that recognize leukocyte membrane molecules. |
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An underactive thyroid can be the result of an auto-immune problem, whereby the body's own antibodies attack the thyroid gland. |
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The presence of antinuclear antibodies was tested by indirect immunofluorescent antibody staining of fixed cells. |
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Serum agglutinins, precipitins, and complement-fixing antibodies can also be used to establish a diagnosis. |
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Your body mistakes undigested food particles for foreign invaders and releases antibodies to fight them. |
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In this method, researchers inject ready-made antibodies, rather than the antigen, into the animal. |
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Your body makes tranquilizers and sleeping pills and immunomodulators and antibodies. |
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The pigments are chemically bonded to antibodies, which are then put into a solution of cells. |
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Viral mutants that are not neutralised by antibodies induced by the available vaccines have been detected. |
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As group O cells do not react with anti-A or anti-B antibodies, people of group O became known as universal donors. |
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Cells were therefore processed for immunofluorescence staining with anti-tubulin antibodies in order to visualize spindle morphology. |
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No disciplinary action was taken because our rules prohibit substances, not antibodies. |
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Try around a dessertspoon a day for one month before the season starts to build up antibodies. |
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However, highly concentrated antibodies may result in a prozone effect, leading to decreased intensity of staining. |
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Passive antibodies transferred across the placenta during pregnancy provide protection for neonates, but this protection is lost fairly soon. |
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Breast milk contains antibodies that protect infants from bacteria and viruses. |
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The secondary antibodies for insulin, glucagon and somatostatin were antirabbit polyclonal antibodies. |
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A survey of immunity in Australian pre-school children has found higher than expected levels of antibodies to measles and German measles. |
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For immunocytochemistry, grids were incubated with the antibodies against macrophages. |
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Cells were harvested and protein extracts were prepared for immunoprecipitation and immunoblotting with the indicated antibodies. |
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At birth, infants have immunity to certain diseases because antibodies have passed through the placenta from the mother to the unborn child. |
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This test is used to identify whether you have pernicious anaemia, as most people who lack intrinsic factor have these antibodies in their blood. |
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The humoral arm produces virus-neutralizing antibodies that, when fully effective, completely prevent virions from infecting new host cells. |
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We chose to consider residue charge because of evidence that the pattern of residue charges is important in determining epitopes for antibodies. |
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With pernicious anemia, the lack of intrinsic factor results from destruction of the gastric parietal cells by autoimmune antibodies. |
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Since coeliac disease runs in families, relatives can have a blood test to check for antibodies. |
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The DAT is usually positive, confirming the presence of IgG antibodies with or without complement on the red cells. |
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Anyone who has antibodies from exposure at the epidemic's height is by definition over 80 years old. |
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An example is a transfusion reaction in which IgG and IgM anti-red-cell antibodies activate complement and cause cell lysis. |
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The remainder of the antibody molecule is more constant between different antibodies. |
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It turns out that the protein, gp 120, is extremely flexible and difficult for antibodies to latch on to. |
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With pernicious anaemia, antibodies damage the cells in the stomach that produce intrinsic factor. |
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The nurse with the hypodermic said the vaccine she would inject in my bicep included antibodies for a flu virus originating in New Caledonia. |
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Colostrum is rich in anabolic peptides, protective antibodies and immune messengers that help the gut heal. |
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We use our host's blood to make antibodies and immunities, added to those we already carry ancestrally. |
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If you've already had it, your body has produced antibodies that fight the virus if you come into contact with it again. |
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Previous attempts to diagnose thromboemboli using radiolabeled antibodies and nuclear medicine imaging have been disappointing. |
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Local government staff took blood samples from each truckload to test for virus antibodies. |
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A healthy body develops antibodies, which hopefully resist the antigens, by binding on them. |
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Most of these analytes are measured by immunoassays using monoclonal or polyclonal antibodies. |
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This is an inactive version of the infection and the body produces antibodies to fight it so that you are then immune to it. |
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You have an immune response to the vaccine as your body develops antibodies to the virus. |
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Our study obviates that criticism, because the antibodies we used are directed toward CXCL12 rather than to CXCR4-bearing NSCLC cells. |
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But if you have hay fever, your body produces antibodies in response to pollen. |
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When a human being becomes immune to an infection, the immunity is usually due to blood cells, lymphocytes, that produce antibodies. |
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In this study specific antibodies against the pathogen Helicobacter were enriched from the colostrum of hyperimmunized cows. |
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The early vaccines focused on antibodies, circulating chemicals in the blood stream which in theory stop HIV locking onto white blood cells. |
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A titer test doesn't measure immunity, but it does measure antibodies circulating in the system. |
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In its attempt to protect the body, it creates specific antibodies to the food. |
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Bcells are white blood cells which defend the body against viruses and bacteria by making antibodies. |
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Immunohistochemistry was performed on an automated immunostainer using the antibodies listed in Table 2 with diaminobenzidine as the chromogen. |
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New therapies based on proteins and antibodies would stop in their tracks chronic diseases such as cancer. |
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If a foal has not suckled after 11 hours there is every chance it will die as the gut wall closes up and the vital antibodies cannot get through. |
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In MS, the fluid may contain white blood cells, high levels of protein and certain antibodies. |
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For example, if you are of blood type A, your body will generate antibodies to attack the B protein. |
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We can reduce levels of that substance by introducing into the body antibodies that specifically recognize it. |
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All of them have been reported to induce antibodies in mice and provide full or partial protection from live virus challenge. |
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When exposed to an antigen, that is a virus or a bacterium, the body produces antibodies. |
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The levels of immune globulins and of certain antibodies in the blood may indicate a problem in the immune system. |
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A blood test can detect antibodies to the hepatitis C virus and a positive test shows that you have been infected. |
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One patient with antiphospholipid antibodies developed a right subclavian and jugular vein thrombosis requiring removal of a Hickman catheter. |
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One pool of GAS surface proteins induced antibodies that were both opsonic and potentially protective. |
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Moreover, Lancefield's studies in 1959 showed that type-specific opsonic antibodies can persist for 10-20 years after a GAS infection in humans. |
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Vaccination is an important part of prevention, providing sheep with antibodies against the causative agent. |
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Authorities detected the first case of Hendra virus antibodies in a dog within a natural environment that same year. |
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Children can achieve or re-achieve detectable levels of protective antibodies after revaccination during combination antiretroviral treatment. |
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Unbound phages were separated from phages bound to antibodies in normal plasma by centrifugation. |
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His lab has developed a chip device that diffracts light in the presence of certain antibodies. |
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As a result, the patient's immune system would produce antibodies to attack the foreign antigens. |
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Immunohistochemistry utilizes antibodies to visualize antigens in sections of tissue under the microscope. |
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Finally, the target antigens of the locally produced antibodies have not been fully identified. |
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However, the specificity of antibodies for antigens has a bearing on one of the issues in this case, and it is for that reason that I mention it. |
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Once antibodies have been produced for a particular antigen they tend to remain in the body. |
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In later pregnancies where the baby is also rhesus positive, the levels of these antibodies in the mother's blood rise rapidly. |
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Some antibodies are antitoxins, which directly neutralize any toxins secreted by the antigens. |
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Arrows indicate cells reactive to the zeatine specific antibodies. |
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In complete contrast, the overactivity encountered in Graves' disease is due to the aberrant production of autoantibodies, known as thyroid stimulating antibodies. |
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The combination of B antibodies and B antigens will cause agglutination. |
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After the pig is weaned, these milk antibodies no longer are supplied. |
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This is a complicated process involving antigens and antibodies. |
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But Jordi found ways, using antigens and antibodies, to figure it out. |
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The cause of male infertility according to the medical model of infertility is due to abnormal sperm parameters, azoospermia and antisperm antibodies. |
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As one would expect, we found that two different antibodies with different antigenic specificities had different amino acid sequences in the antigen-binding site. |
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It has developed proprietary monoclonal antibodies to properdin that are potent in vitro and in vivo inhibitors of the complement alternative pathway. |
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They are also biocompatible, and their surfaces can be modified to attach antibodies or other ligands that could be used to target the nanoparticles to specific tissues. |
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If these antibodies are effectively antitoxic, the studies could then lead towards molecular approaches for producing human antibodies for therapeutic purposes. |
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Fifty-one of 77 patients tested negative for all the antibodies examined. |
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For example, antitoxins, like tetanus antitoxin, are made by injecting horses with a small amount of the toxin so that the animal produces the antibodies. |
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This advice follows a specific episode last Autumn where antibodies to the EVA virus were identified in a number of homebred unvaccinated equines. |
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To answer those questions, Fuchs and her colleagues first isolated stem cells from the bulge by fusing antibodies to characteristic cell surface molecules. |
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The results of an autoantibody screen and testing for antineutrophil cytoplasmic antibodies were negative, complements were normal, and cryoglobulins were not detected. |
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The use of targeting antibodies conjugated to enzymes that selectively activate antineoplastic prodrugs on or near cancer cells is also addressed. |
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Animals can be injected with antigens so they will produce the desired antibodies, but it is difficult to extract them from among the many types produced. |
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It is unusual for a neuroendocrine tumour to secrete more than one hormone, so we considered whether the patient could have heterophilic antibodies. |
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We recommend that mold-exposed individuals with symptoms of neuropathy be evaluated for antibodies against neural antigens and for neurophysiological abnormalities. |
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As mentioned earlier, IgM antibodies to various neural antigens have been associated with neurophysiological and pathological changes characteristic of various neuropathies. |
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Serum antibodies to capsular polysaccharides confer protection against meningococcal disease by activating complement-dependent bacteriolysis and, possibly, by opsonization. |
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Those results led the authors to believe that either patients were exposed simultaneously to the 3 molds, or that these antibodies were the result of cross-reactive antigens. |
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The putative motor protein, cross-reacting with antimyosin antibodies, was shown to be associated with the surface of isolated Lemna chloroplasts. |
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Though significantly high titres indicate an acute infection, rise in titres of antibodies in serum samples collected one week apart is diagnostic. |
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Many antibodies used in diagnostic immunoassays are derived from rabbits. |
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Your immune system fought it off, created chicken-pox antibodies, and protected you from getting it again. |
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Six months later, the researchers found, the subjects who showed the most activity in the brain's right prefrontal cortex also had the lowest antibodies. |
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For example, fluorescent cyanine and related dyes can be attached to amine, hydroxy or sulfhydryl groups of avidin and to antibodies and to lectins. |
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By the time the rash or polyarthropathy presents in immunocompetent patients, viremia has cleared and the presence of serum antibodies confirms the diagnosis. |
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Supporting this is the discovery by Vojdani et al., who reported that some individuals develop allergic antibodies to haptens formed in response to MTBE binding to albumin. |
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When used in a vaccine, these pieces of carbohydrate stimulate the immune system to make antibodies against the real carbohydrate targets on the bacteria. |
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This resulted in polyclonal activation of the immune system because the antibodies of these mice reacted with 6-12 compounds of the tularaemic antigen. |
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Hall validated her observations by staining the cells with various antibodies that only bind to and illuminate proteins unique to oligodendrocytes precursor cells. |
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In other research, scientists will test the theory that there are natural antibodies in epithelial cells lining the mouth that protect against dental caries. |
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A secondary goal is to assess how well the vaccine stimulates the immune system to produce antibodies and cellular immunity, in this case, focusing on the SARS spike protein. |
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All mothers had been tested for HIV antibodies and were HIV seronegative. |
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As we did not serotype these pneumococcal strains or measure antibodies to them, we cannot do more than speculate on the mechanism for this observation. |
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How did opsonic antibodies enhance alveolar macrophage effectiveness? |
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The colostrum supplies antibodies needed by the foal to fight off disease, and these antibodies are absorbed through the gut only during the first 24 hours of life. |
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Other systemic therapies include monoclonal antibodies, protein specifically targeting memory T cells, fumaric acid esters, novel retinoids, and macrolactams. |
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In humans and animals only M protein typespecific antibodies have the capacity to opsonize streptococci and to override the anti-phagocytic property of M protein. |
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The role of B-cells in the immune response is to release antibodies that may opsonize a particular cell and assist T-cells in destruction of that cell. |
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It had become a laboratory standard or reference strain for raising antibodies and for challenge in virus neutralization test to detect and assay antibody in serum. |
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Rather, all of the manufactured antibodies are all stirred up but have nowhere to go. |
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Mother's milk is full of special nutrients, hormones and antibodies that are passed on to infants to help them to resist infections, respiratory illness and diarrhoea. |
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Then the researchers checked for blood levels of influenza antibodies a month later. |
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Some individuals with clinical disease have no such antibodies detectable. |
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Tests for blood chemistry, hematology, and immunology were unremarkable except for elevated immunoglobulin E antibodies to environmental allergens. |
|
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According to those who witnessed the transfusion, the effects of the antibodies were seemingly evident within hours. |
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Even if you know you have had the rubella vaccination, your body may not have made enough antibodies to make you immune to the virus, so it is best to check. |
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Thus, we evaluated these patients for the presence of antibodies to 9 neural antigens, as well as for evidence of abnormalities in peripheral nerve conduction. |
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Four weeks after the injections, all 20 of the participants had developed the antibodies needed to stave off the infection. |
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Autoantibodies such as antinuclear antibodies and myositis-specific autoantibodies bind to proteins normally present inside one's own normal skin and muscle cells. |
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Briefly, the assay is based on the detection of an immunoreaction between sTfR and sTfR-specific antibodies in liquid phase. |
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Analysis of CD59 antibodies on antiglycophorin A gated erythrocytes was used to identify erythrocyte PNH cone size. |
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The phosphorylation levels were detected with antiphosphorylated antibodies by Western blot analysis. |
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The cells were fixed and coimmunostained with the centrin-2 and CEP135 antibodies. |
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Antimyelin antibodies are produced in an extrathecal site, as occurs in Sydenham's chorea. |
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These questions will need to be addressed using mono-specific AhLPAT2 antibodies and immunomicroscopic analysis of native peanut tissues. |
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Immunoselection involves the use of an antibody or a collection of antibodies. |
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Upon treatment with Digitonin, exogenously added antibodies have no access to intraorganellar proteins as these are shielded by the membrane. |
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Based on the reactions of the patient's serum against the donor cells, a pattern will emerge to confirm the presence of one or more antibodies. |
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The immunological reaction occurs when the receiver of a blood transfusion has antibodies against the donor blood cells. |
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A vaccine non-responder is a person who does not develop protective surface antibodies after completing two full series of injections. |
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Thus, in contrast to the indigenous people, Europeans had developed a richer endowment of antibodies. |
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Thirdly, diagnostic methods that rely on the detection of antibodies are more likely to fail. |
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A broad, sensitive test for pathogens that detects the presence of infectious material rather than antibodies is therefore highly desirable. |
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Camels, in addition to these, also have antibodies made of only two heavy chains, a trait that makes them smaller and more durable. |
|
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These pancreatic cell antibodies react with human cell surface molecules on alpha, beta, acinar and duct cells. |
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Comparison of the direct radiolabeled antiglobulin assay and the direct immunobead binding test for detection of sperm-associated antibodies. |
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Clinical correlations of antibodies that bind, block, or modulate human acetylcholine receptors in myasthenia gravis. |
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Our second line of defence is made up of the cells and antibodies of our adaptive immune system. |
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Moreover, they had no reaction to antibodies against pituitary hormones, such as adrenocorticotrophic hormone, growth hormone, and prolactin. |
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Subsequently, Kirin and Hematech have progressed to developing cows that can efficiently produce human antibodies. |
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She agrees with her colleagues that most antibodies against HIV are not effective. |
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Immunohistochemical diagnosis of systemic bovine zygomycosis by murine monoclonal antibodies. |
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Antinuclear antibodies were absent, and angiotensin-converting-enzyme values were normal. |
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Tests for human immunodeficiency virus infection and serum antinuclear antibodies were also negative. |
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Antitoxins usually consist of antibodies made by injecting a toxin into animals and allowing their immune system to respond. |
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Kawasaki disease is often treated with transfusions of blood rich in antibodies, but it is not known if Jett underwent such therapy. |
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Blood samples collected from the specimens were tested for evidence of IgG antibodies to New World hantaviruses and arenaviruses. |
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The development of such antibodies can cause red blood cell destruction if red blood cells with the corresponding antigens are later transfused. |
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Sidestepping antibodies and focusing on killer T cells seemed like a practical alternative, Letvin says. |
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Lupus-like syndrome, Quincke's edema, laryngitis and stomatitis occurred only in the antibodies to Tumor Necrosis Factor-alpha recipients. |
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Defra said blood tests carried out on a flock bought to restock a farm in Kirby Stephen, Cumbria, detected positive antibodies in the one animal. |
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If IgE antibodies expressed on the basophils are specific to the allergen, activation occurs and inflammatory mediators are released. |
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For wound care, the researchers suggest, the biosensor pores would contain molecules, such as antibodies, that bind to microbe-specific proteins. |
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High levels of antibodies to the virus were also found in people trading masked palm civets, which are considered a delicacy in parts of China. |
|
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In this study, T gondii antibodies were detected in 4 bird species and in a giant anteater for the first time. |
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Serodiagnosis of human paragonimiasis by ELISA-inhibition test using monoclonal antibodies. |
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Conventional serological tests are done based on the presence of antibodies and they take up to two to six weeks to give the correct result. |
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They've also developed a vaccine injection that produces methanogen antibodies in saliva, which would then travel into the rumen. |
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Further antibody and serology testing of anti microsomal antibodies, thyroglobulin, Lyme serology, and perineoplastic antibodies were negative. |
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The antigen, two antibodies, and the enzyme form a tetrametric complex to generate the ELISA signal. |
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In the years since, catalytic antibodies, sometimes called abzymes, have attracted commercial, scientific, and medical interest. |
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Candidate binding groups include aliphatic quaternary amines, organophosphate complexing agents, chelating agents, crown ethers or antibodies. |
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The IgA antibodies also provide a substrate that allows our mutualist bacteria to form the biofilms that line and protect the colon and appendix. |
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The myofilament lattice collapse in these embryos has been analyzed by immunofluorescence with antibodies to myosin A and actin. |
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Results of serologic testing for nanobacteria were also unconfirmed because they were based on nonspecific antibodies. |
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The clinical diagnosis was supported by seroconversion to protective antigen and the presence of antibodies against lethal factor. |
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Development of a standardized subgrouping scheme for Legionella pneumophila serogroup 1 using monoclonal antibodies. |
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The SARS coronavirus propagated in Vero-E6 was used as an antigen to test whether SARS-coronavirus antibodies were raised in sera. |
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Citrullinated peptides are found in the synovial membranes of many arthritis patients, but only RA patients produce anti-CCP antibodies. |
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Harmful effects of anti-zona pellucida antibodies in folliculogenesis, oogenesis, and fertilization. |
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Generally, protection against GAS infection has been correlated with presence of type specific opsonic antibodies against M protein. |
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Such patients have multiple serological abnormalities like anticardiolipin antibodies, cryoglobulins, and hypocomplementemia. |
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Each vaccine prompts the immune system to produce antibodies against the hemagglutinin and, therefore, against the virus. |
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Identification of Bacillus anthracis by polyclonal antibodies against extracted vegetative cell antigens. |
|
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Anti-liver cytosolic antigen type 1 antibodies in childhood autoimmune liver disease. |
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Identification of human neutralizing antibodies that bind to complex epitopes on dengue virions. |
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Vitellogenin uptake and vitellin localization in insect follicles examined using monoclonal antibodies and confocal scanning microscopy. |
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The antibodies in this kit have been raised to detect these denatured proteins. |
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In one of our earlier experiments we had found that gliadin antibodies cross-reacted with instant coffee. |
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Newborn calves acquire passive immunity by ingestion and absorption of antibodies present in colostrum. |
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ImmunoDetection assays rely on patented perfusive media, using these media with antibodies immobilized on solid surfaces. |
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Characterization of periplasmic protein BP26 epitopes of Brucella melitensis reacting with murine monoclonal and sheep antibodies. |
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Immunogenicity of synthetic angiotensin II octapeptide and analysis of antibodies by passive haemagglutination. |
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Although monoclonal antibodies have reasonably long half-lives, market pressures for less frequent dosing schedules can reduce efficacy. |
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The neat and diluted antibodies were pipetted in tandem using two pipetting techniques. |
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In Kampala, Uganda, in 2001, hepatitis C virus antibodies were found in 27 of 603 children and in 62 of 525 of their mothers. |
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Mosquito collection in heronries and antibodies to Japanese encephalitis virus in birds in Asansol-Dhanbad region. |
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In this study, we compared a capture ELISA for PR3 and MPO antibodies with a new, commercially available DB method. |
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Endomysium antibodies in the diagnosis of celiac disease in short-statured children with no gastrointestinal symptoms. |
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IgM, IgG and IgA class enterobacterial antibodies in serum and synovial fluid in patients with ankylosing spondylitis and rheumatoid arthritis. |
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Differential diagnosis of chordoma, chondroid, and ependymal tumors as aided by anti-intermediate filament antibodies. |
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Humoral immunity involves the recognition of extracellular antigen by B lymphocytes bearing antigen-specific antibodies on their surface. |
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Humoral immunity is provided by antibodies that circulate in the blood and lymph. |
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A drop of human blood is presumed to have 10e11 specific antibodies that recognize different immunogens. |
|
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This new instrument can accelerate and enable the discovery of diverse antibodies from primary B-cells or hybridomas. |
|
Hybridomas or other cell lines expressing such immunoglobulin molecules and monoclonal antibodies are also provided. |
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The reactivity of the antibodies produced by the hybridomas was then determined. |
|
The technology includes monoclonal antibodies and related hybridomas and other related know-how. |
|
Autoimmune hepatitis is a non-resolving inflammatory hepatitis with hypergammaglobulinaemia and liver related auto antibodies in the serum. |
|
Lupus anticoagulants cause a prolongation of the aPTT, probably as a result of hypoprothrombinemia induced by antiprothrombin antibodies. |
|
Calcium has also been studied because of suggestions that excitotoxicity and calcium channel antibodies may be implicated in its etiology. |
|
In addition, there is growing interest in the IgA class anticardiolipin antibodies. |
|
The vaccine is immunogenic and antigen dose-dependent induction of antibodies has been confirmed for all three proteins, the company said. |
|
Also known as antibodies, immunoglobulins are produced by the body to attach and destroy bacteria, viruses, fungus, and other foreign substances. |
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This reference provides information on pharmaceutical and pharmacological characteristics of antibodies, vaccines, and other immunologic drugs. |
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Diagnosis is confirmed by detecting antierythropoietin antibodies using immunoprecipitation. |
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Proteins also provide life-sustaining enzymes, immunoproteins, or antibodies and peptide hormones that control many body functions. |
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Immunization with antigenized antibodies is an efficient method to focus the immune response against defined epitopes of foreign antigens. |
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Immunotoxins made with the antibodies and antibody fragments of the invention have improved cytotoxicity to CD22-expressing cancer cells. |
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They then introduced special antibodies with toxins and found that the immunotoxins penetrated the leukaemia cells and killed them faster. |
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But women who test positive for chlamydia antibodies have little way of knowing whether the infection has scarred their fallopian tubes. |
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Staining was not seen in serial sections stained with the isotype antibody or with no antibodies. |
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Hepatitis b,quick test detection of antibodies to treponema pallidum,thromboplastin time with partial vacuum tube sodium citrate 2ml. |
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In traditional radioimmunoimaging, radioisotopes are linked directly to antibodies and are delivered together to tumour targets. |
|
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Anti-SS-B, anti-smooth muscle antibodies, cardiolipin antibodies and antimitochondrial antibodies were negative. |
|
In contrast, immunohistochemistry uses specific antibodies to provide information on protein expression, including which cell types express the protein. |
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Immunoglobulins or humoral antibodies are a group of structurally related proteins that recognize the antigens and initiate mechanism that destroys them. |
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Passive transfer of antibodies protects immunocompetent and immunodeficient mice against lethal Ebola virus infection without complete inhibition of viral replication. |
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Serological cross-reactivities between antibodies to simian virus 40, BK virus, JC virus assessed by virus-like-particle-based enzyme immunoassays. |
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The RapidWN uses solid-phase immuno-chromatographic strip technology to qualitatively detect the presence of WNV IgM antibodies in human serum or plasma. |
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Owing to the low levels of IgM antibodies after vaccination, commercially available tests rarely detect these antibodies unless the sample dilution is decreased. |
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Moreover, even if testing is done, it may not be at the optimal time, that is, the antibodies may not yet have been induced or may have already evanesced. |
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NeutroSpec contains both murine antibodies and sodium hydrosulfite, each of which has been known to induce allergic reactions, including anaphylaxis. |
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Balance between survivin, a key member of the apoptosis inhibitor family, and its specific antibodies determines erosivity in rheumatoid arthritis. |
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Seorsurvey of West Nile virus antibodies in equids and bovids in Spain. |
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In this study, commercial anticTnI MAbs specific to different epitopes were used as capture antibodies in sandwich immunoassays with an anti-troponin C MAb used as a tracer. |
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However, only few studies have investigated antibodies as potential EP-blocking-agents that may potentiate antimicrobial sensitivity in XDR bacteria. |
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The fractionated proteins were electrophoretically transferred to an immobilon polyvinylidene difluoride membrane and probed with the appropriate antibodies. |
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Epstein-Barr virus genomic sequences and specific antibodies in cerebrospinal fluid in children with neurologic complications of acute and reactivated EBV infections. |
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The pattern of neutralizing antibodies and IgM in acute-phase and convalescent-phase serum samples is evidence of recent exposure to a henipavirus. |
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A decrease in anti-AChR antibody concentration may have been caused by CPB institution, hemodilution, and adsorption of antibodies to the pump components. |
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Single dilution ELISAs using soluble piroplasm, cellular schizont and soluble schizont antigens for the detection of antibodies against Theileria annulata. |
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Continuous, perfusion bioprocessing is not really new, and has been used for decades for commercial biologic manufacture, including blockbuster monoclonal antibodies. |
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One of these new assays detecting IgA antibodies to the fibrillar form of the depolymerized actin protein of the cytoskeleton is promising but not completely defined. |
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