Under these irradiation conditions, another major class of oxidative damage occurs, namely the formation of covalent protein-DNA adducts. |
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A highly sensitive method first developed for carbon dating, AMS quantifies isotopes with a detection limit of a few adducts in 10 nucleotides. |
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Biological monitoring of isocyanate is possible using albumin adducts and their corresponding diamines in plasma and urine. |
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Purified lipid-DNA adducts had a characteristic fluorescent spectra and showed a decrease of hyperchromicity and melting point. |
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It has been known for some time that smoking can give rise to acrylamide in human red cells that forms adducts with haemoglobin. |
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Rodents eating unfried pancakes had only one-tenth that concentration of acrylamide adducts. |
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In rat liver, it has been shown that tamoxifen forms covalent DNA adducts, implying a genotoxic mechanism for its carcinogenicity in this tissue. |
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This maneuver adducts the fetal posterior shoulder in an attempt to rotate the shoulders out of the impacted position and into an oblique plane for delivery. |
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These include the single cell gel electrophoresis assay, the gel electrophoresis assay, the alkaline elution and unwinding assays and the analysis of DNA adducts. |
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Moreover, some photoactivable compounds can also produce bulky adducts. |
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The structural and thermodynamic features of these stereoisomeric adducts are also discussed in relation to their reported low susceptibilities to nucleotide excision repair. |
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Nitrogen-15 NMR detection of ketones via their oxime derivatives and quinones via their anilinohydroquinone adducts overcomes this problem. |
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Alcohol metabolism leads to hepatic oxygen deficits, adducts and ROS formation, and interaction between alcohol metabolites. |
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Balbo pointed out that people have a highly effective natural repair mechanism for correcting the damage from DNA adducts. |
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Glycosylated fractions and other posttranslational adducts separate from the main peaks, making the chromatogram somewhat challenging to interpret. |
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Comparison of binding kinetics, binding sites and reactivity of the Pt-protein adducts of Cisplatin and transplatin towards biological nucleophiles. |
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Online analysis of TTR by MS does not allow for the reduction step and the subsequent desired simplification of the mass spectrum by elimination of multiple adducts. |
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Because EDTA is a well-known chelating agent, it is worth speculating that chelation of iron would stabilize benzoquinone adducts, possibly by inhibiting Fenton chemistry. |
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The nonstereospecificity and methanol adducts observed during the reaction of MTAD with the Z,Z isomer suggest the involvement of an open zwitterion. |
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