| Clofarabine, a type of drug called a purine nucleoside antimetabolite, works by blocking the production and repair of DNA, the building blocks of genes. |
| Neither of the two NIH scientists knew the name or chemical compound of AZT at the time or that it was a nucleoside analogue. |
| Previously treated with three classes of antiretrovirals: nucleoside analogues, non-nucleoside reverse transcriptase inhibitors and protease inhibitors. |
| Nonpolar nucleoside isosteres have proven broadly useful in the study of DNA replication by a wide variety of polymerase enzymes. |
| In January 2001 the Food and Drug Administration issued a special warning to pregnant women taking nucleoside analogues ddI and d4T after three women died. |
| We assessed the clearance of endogenous pseudouridine in humans to evaluate the potential use of this modified nucleoside as a marker of glomerular filtration rate. |
