| Eating DMT fails because monoamine oxidase in the gut metabolises the tryptamine into secondary compounds which lack any psychoactivity. |
| The five designer drugs included in the list of prohibited drugs are synthetic cannabinoids, synthetic cathinones, phenethylamine, piperazine and tryptamine. |
| The yucca phenotype derives from overexpression of a flavin monooxygenase like enzyme that oxidizes tryptamine to N-hydroxyl-tryptamine in vitro. |
| These include tyramine, tryptamine, phenylethylamine, and serotonin. |
| Studies of this FMO-like enzyme in yucca revealed that the enzyme most likely catalyzes the oxygenation of the compound tryptamine. |
| They suggested that elevations in serotonin and tryptamine were responsible for the clinical symptoms see with this syndrome. |
