| The precise relationship between test substance-induced delay of ventricular repolarization and risk of proarrhythmia is not known. |
| An abnormality of cardiac muscle repolarization, defined as the time from Q wave deflection to the end of T wave on an electrocardiogram. |
| Ion exchange is required for depolarization, reestablishing intracellular homeostasis, and cell repolarization. |
| There are, therefore, both depolarization and repolarization waves represented in the electrocardiogram. |
| Dolasetron appears to prolong both depolarization and, to a lesser extent, repolarization time. |
| Ventricular repolarization, determined by the duration of the cardiac action potential, is a complex physiological process. |
