Selective activity of polyene macrolides produced by genetically modified Streptomyces on Trypanosoma cruzi. |
A protein-bound polyene chromophore is not the same as a polyene trapped within the cavity of an amorphous solid. |
During equilibration the structure was stable and retinal assumed a fairly planar conformation, which showed a mild twist distributed over the main chain of the polyene. |
Nystatin is a polyene antifungal drug that binds directly to ergosterol in the cell membrane. |
As the chromophore is a polyene, there are several double bonds capable of isomerization. |
Among alkenes, mono-alkene constituted the largest proportion, while the ratio of alkadiene and polyene was quite small. |