| In particular, there is potential for a neurotoxic metabolite, normeperidine, to accumulate and cause seizures, myoclonus and tremors. |
| Reported neurological manifestations have included tremor, myoclonus, hyperreflexia, ankle clonus, muscle rigidity, ataxia and incoordination. |
| Other but less frequent motor symptoms include paratonic rigidity, asterixis, tremor and multifocal myoclonus. |
| We report on 15 patients in whom benign sleep myoclonus was initially mistaken for epilepsy. |
| If several muscles are implicated, the condition is one of multiple myospasm or myoclonus. |
| The acute effects are coma, myoclonus and bradycardia, which generally resolve rapidly without complication. |
