| Both monosomy and trisomy of specific chromosomes are associated with developmental defects and cancer risk. |
| Isochromosome 17 in this tumor may be functionally equivalent to monosomy 17, as the short arm is lost. |
| Similarly, monosomy for any of the autosomes is lethal in utero and therefore is not seen in the population. |
| An example of monosomy is monosomy X, or 45X, which is also known as Turner's syndrome. |
| The predominant anomalies in reproductive specimens include trisomy of the autosomes and monosomy of the X chromosome. |
| We conclude that chromosomes with damaged centromeres fail to correctly attach to the spindle, thus producing MN and monosomy. |
