| The current study investigates autoantibodies against steroid synthesis enzymes in dogs with spontaneous hypoadrenocorticism. |
| This study demonstrates persistence of P450scc autoantibodies in a subset of dogs affected with hypoadrenocorticism and seroconversion over one year post-diagnosis. |
| Autontibody persistence in dogs with hypoadrenocorticism might represent persistent pathology, due to residual antigenic stimulation and autoimmune inflammation in the adrenal gland. |
| Addison's disease, also referred to as chronic adrenal insufficiency or hypoadrenocorticism, has been reported in many individual dogs. |
| The current study was designed to investigate changes in serum P450scc autoantibody status over time in dogs diagnosed with spontaneous hypoadrenocorticism. |
| White blood cell count and the sodium to potassium ratio to screen for hypoadrenocorticism in dogs. |
