| The 25-bp insertion causes a frameshift mutation and creates stop codons in all three reading frames. |
| We estimate that reversion of the lac mutation is about one-tenth as likely as a null frameshift mutation in a typical gene. |
| Of these, the recurrent frameshift mutation of HDAC2 in exon 1 has been the most extensively characterized. |
| A deletion in exon 6 at codon 260 results in a frameshift mutation and complete loss of hydrolytic activity. |
| This transgenic mouse model targets expression of truncated decorin to keratocytes, thereby mimicking the human frameshift mutation. |
| This frameshift mutation could be merely drifting to high frequency due to weak functional constraint. |
