| Endotoxemia and sepsis also induce mitochondrial dysfunction, sarcolemmal injury, and weakness and fatigability of the diaphragm. |
| Physical fatigue or fatigability is focal muscle fatigue that occurs with persistent activity, such as a limp with walking. |
| The loss of aerobic capacity and muscle tone through inactivity can lead to easy fatigability or exertion as well as to lassitude. |
| Chronic backache usually involves a loss of muscle strength and above all, heightened fatigability of back muscles. |
| If these changes were of sufficient magnitude, they would clearly be expected to increase muscle fatigability. |
| Physical activity, leg muscle fatigability, calf muscle flexibility, and leg volume also were measured at the start of the study. |
