| The cost of generic diclofenac, a widely used NSAID in Canada, was used as the input for the cost of nonselective NSAIDs in all treatment arms. |
| Generic Voltaren is a NSAID used to relieve the inflammation, swelling, stiffness and joint pain. |
| However, the impact of prolonged bleeding and reduction in inflammatory response needs to be considered before commencing NSAID therapy. |
| The medication is used to treat stomach and duodenal ulcers, ulcers caused by NSAID or stress, hyperacid gastritis, reflux esophagitis, reflux gastritis, gastroduodenitis, heartburn. |
| Tramadol is not an NSAID and thus does not have an increased risk of serious gastrointestinal injury. |
| Non-selective NSAID therapy may be appropriate for chronic pain management in aspirin users given that suitable GI prophylactic measures are utilized in high-risk patients. |
