However, we were able to examine the transport of the anti-hSC Fv-based fusion proteins from the circulation to the lumenal surface of human epithelia in tracheal xenografts. |
In terms of the biology of the tissue, more vascularized organs, xenografts, and non-pretreated fresh grafts all lead to a severe host response. |
Concern has centered on the risk of introducing novel pathogens derived from animals into human recipients of xenografts. |
The H-MESO1 xenografts used in these studies were grown s.c. in a mouse host, and some necrosis was evident as the tumors grew. |
Complement-mediated rejection of nerve cell xenografts presents an important obstacle to effectively replacing damaged cells in the central nervous system. |
Of the six kidney xenografts performed that year, all six suffered cellular rejection within the first 60 days. |