These data confirm that cycloaddition occurs between the 8,9-double bond of HFQ and the 5,6-double bond of thymine. |
These bases are adenine, cytosine, guanine and thymine and can be represented as A, C, G, and T, respectively. |
Insertion of the thymine moiety into the angelicin skeleton caused a folding of about 51 of the cyclohexyl moiety. |
Carmel's group looked for places in the ancient DNA where cytosines had morphed into thymines. |
Ultraviolet radiation joins adjacent thymines, creating thymine dimers, which, if not repaired, may cause mutations. |
Special repair enzymes either cut the bond between the thymines or excise the bonded dimer and replace it with two single thymines. |