| Pulmonary function testing, including spirometry and whole-body plethysmography, was performed at each visit. |
| Before and after training, spirometry, plethysmographic lung volumes, and carbon monoxide diffusing capacity were assessed. |
| A written symptom diary was completed each morning, and spirometry was performed twice daily. |
| Between 1964 and 1974, the spirometry was performed with the McKerrow spirometer. |
| During the two-week run-in period, patients underwent spirometry and recorded daily symptoms and morning peak-flow measurements. |
| After 2 to 4 weeks, they had spirometry, sputum induction, and a methacholine inhalation test. |
