| Efficient oncolysis by a replicating adenovirus in vivo is critically dependent on tumor expression of primary ad receptors. |
| Gene therapy and viral oncolysis represent treatment modalities that offer unique opportunities for tumor targeting. |
| Eleven of 16 cell lines were moderately to highly sensitive to G207 viral oncolysis. |
| The oncolysis induced by PA via apoptosis was exhibited clearly the involvement of Bax and Bcl2 both at protein level and gene level. |
| Strains of VSV that induce or direct the production of interferon are superior to wild-type strains of the virus for inducing oncolysis. |
| But biologic treatments such as angiogenesis inhibition, viral oncolysis, and gene therapy are more promising in the long term. |
