| Rare cases of rhabdomyolysis with acute renal failure secondary to myoglobinuria have been reported with CRESTOR and with other HMG-CoA reductase inhibitors. |
| In this setting, a serum sample with normal color indicates myoglobinuria, whereas a pigmented brown or red serum sample indicates hemoglobinuria. |
| Myopathy sometimes takes the form of rhabdomyolysis with or without acute renal failure secondary to myoglobinuria, and rare fatalities have occurred. |
| Urinalysis showed no haemoglobinuria suggestive of myoglobinuria. |
| If SCr is elevated, CK is greater than 10 times the ULN, or there is myoglobinuria, this is rhabdomyolysis. |
| However, when correctly conducted, the test may be important with regard to determining the risk of acute kidney failure, an important complication of massive myoglobinuria. |
