An organism is defined through the set of preferred codons shaping its genome. |
In effect, the DNA blueprint is a succession of code words, each consisting of a set of three nucleotides, known as codons, in the gene. |
Due to the redundant nature of codons, the genetic code shows a significant level of neutrality. |
The only exception to this rule is that transitions to stop codons are disallowed. |
The 25-bp insertion causes a frameshift mutation and creates stop codons in all three reading frames. |
Biochemistry may explain why most of the exceptions to the genetic code involve stop codons. |