“The reaction mixtures were subsequently dialyzed against 100 mM ammonium acetate solution at pH 7.4 in the dark followed by lyophilization.”

“After fractionation with ammonium sulphate the sample was dialysed against ammonium bicarbonate buffer for desalting and lyophilization.”

“Cell debris was pelleted by centrifugation and supernatant concentrated by lyophilization to one tenth of the initial volume.”

“The aqueous extract was drained, frozen, and placed on a lyophilizer until all water was removed.”

“The company has also expanded from that one lyophilizer in 1997 to the 26 they use today, making them the CMO with the largest lyophilization capacity on the east coast.”

“The Virtis Benchmark 3000 lyophilizer provides thirty-six square feet of shelf area and can support production runs of up to 13,000 vials per campaign.”