| It is common in children with xeroderma pigmentosum, who are unable to repair DNA damage caused by ultraviolet irradiation. |
| Trial use of the UV monitor by five xeroderma pigmentosum patients started in June 2000 and was carried out for 1 year. |
| The xeroderma pigmentosum derived fibroblast cell line spectra also showed non-significant results when compared with each other. |
| A well-known example is xeroderma pigmentosum patients, who are deficient in excision repair and have a high incidence of skin cancer on exposure to sunlight. |
| Defects in NER are known in humans, in the form of the rare genetic disease xeroderma pigmentosum, which is characterized by extreme sun sensitivity and skin cancer incidence. |
| Further evidence for the importance of DNA repair processes in skin cancer induction stems from numerous observations in patients suffering from xeroderma pigmentosum. |
