In sickle cell disease, the amino acid valine is substituted for glutamic acid in the beta-hemoglobin chain of hemoglobin. |
The formyl termini have been patched onto the last valine residue in the sequence of each monomer. |
Branched-chain amino acids are composed of leucine, isoleucine and valine, three of 18 amino acids that make up a complete protein. |
Sickle cell anemia is caused by a mutation from a glutamate to a valine in the beta chain of the hemoglobin molecule. |
The aspartate can be used as a precursor for the synthesis of other amino acids such as asparagine, threonine, isoleucine, leucine, valine, lysine, and methionine. |
Glycine and valine exhibited isotopic values outside the range of our sampled end members. |