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What does upend mean?

Looking for the meaning or definition of the word upend? Here's what it means.

Verb
  1. (transitive) To end up; to set on end.
  2. To tip or turn over.
  3. (figuratively) To destroy, invalidate, overthrow, or defeat.
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Examples
It is a revolutionary story, which threatens to upend the world as we know it.
It would inject a threat of accountability into power, and upend the impunity wartime leaders had operated under for years.
First, he wants to upend the conventional league tables that rank the foreign policies of modern American presidents.
There was lifting to it —though Wally Lewis says there was no intent to upend him dangerously— but the tackle is on report.
In August, Sen. Ted Cruz linked the need to upend the IRS to its abuse of power.
The clock can circumrotate 360 degrees and the LCD time display will never upend.

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