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What is a tranquilliser?

What is a tranquilliser? Here are some definitions.

Noun
  1. Non-Oxford British English standard spelling of tranquilizer.
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Examples
Even a prescription of the tranquilliser diazepam failed to calm her nerves.
The use of any allopathic tranquilliser, prior to and during transport, is prohibited.
Government workers tried to catch the creature by laying cages and shooting it with tranquilliser darts, but they failed.
We follow a group of zoologists and trackers into a forest where, spying their quarry, a wild, naked girl, they shoot her with tranquilliser darts.
The basis of my argument was that Diazepam is not an anti-depressant but a tranquilliser, which you had incorrectly reported.
Mr President, perhaps the medical service could give the honourable gentleman a tranquilliser.

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