| This superfamily, called Dene-Caucasian, was probably used throughout Eurasia before either Nostratic, or Eurasiatic, spread. |
| All members of the superfamily share the same pentameric quaternary structure. |
| The superfamily currently comprises 19 families, approximately 89 subfamilies, and about 21,000 described species. |
| The serotonin type 3 receptor is a member of a superfamily of ligand gated ion channels. |
| The cytochromes P450 are a superfamily of haemoproteins that catalyse the oxidation of a number of endogenous and xenobiotic substances. |
| Talin, merlin, and philopodin are other major members of the FERM superfamily. |
