Sanaria's mission is to develop and commercialize live, whole sporozoite vaccines against malaria. |
Maturation of the oocysts leads to sporozoite release into the hemocoel. |
The sporoplasm, representing the sporozoite, is always single. |
The parasite, in a form called the sporozoite, moves with the mosquito's saliva into the human bloodstream. |
Sanaria has pioneered the manufacture, storage, shipping, and administration of Plasmodium falciparum sporozoite stage malaria parasites as vaccines. |
Plasmodium sporozoite protein with a membrane attack complex domain is required for breaching the liver sinusoidal cell layer prior to hepatocyte infection. |