Two of the affected seminiferous tubules contain numerous macrophages phagocytosing sperm, whereas only a few remaining spermatogonia can be identified. |
In severely degenerated tubules, only spermatogonia and Sertoli cells were observed, and pachytene spermatocytes sloughing into the lumen were observed. |
There were still a few spermatogonia attached to the follicular walls, whereas spermatocytes were rarely found in the follicles. |
Spermatogonia are the mitotic germ cells of the testis from which sperm arise by spermatogenesis. |
The outer rim of the testis was occupied by zones containing spermatogonia, while zones containing spermatocytes and spermatids were situated internally. |
Males are consequently exposed to new antigens when spermatogonia mature, and the immune activity involved in the male reproductive system may lead to autoimmunity. |