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What does run the gauntlet mean?

Looking for the meaning or definition of the word run the gauntlet? Here's what it means.

Verb
  1. Used other than with a figurative or idiomatic meaning: see run,‎ gauntlet.
  2. (idiomatic) To undergo a series of tests or challenges.
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Examples
A calcium ion has to run the gauntlet of many, many molecules before it reaches a binding site.
The very fact the woman had to run the gauntlet of traffic and pigeons messing on her is proof alone she is not experiencing a level playing field.
Trucks bringing in supplies have to run the gauntlet of Isis checkpoints and ambushes.
Also, women collaborators were forced to run the gauntlet and were really beaten.
To run the gauntlet of their faces in Cornhill is enough to discourage a thoughtful man for hours.
Not only this, but in my individual case no bus was prepared to run the gauntlet.

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