They speculate that the radiation will work in much the same way it does when used to prevent restenosis from occurring in arteries in the heart. |
In preclinical and clinical studies at cytostatic doses, paclitaxel has demonstrated promising results for reducing the processes leading to restenosis. |
In either case, the artery suffers restenosis, or narrowing to the point where healthy blood flow is again impaired. |
Exercise testing performed with myocardial perfusion imaging improves the sensitivity and specificity for the detection of restenosis. |
However, in similar coronary artery studies, antiplatelet treatment has no effect on restenosis compared with placebo. |
Research has focused on developing methods to reduce or eliminate the potential for restenosis, including drug-eluting stents and radiation therapy. |