| The rabbit pyrogen test is well established as an official end-product test. |
| The most widely known pyrogen is the endotoxin lipopolysaccharide, which is produced by gram-negative bacteria. |
| The most important pyrogen is endotoxin, a constituent of the cell wall of gram-negative bacteria that can generate endogenous fever mediators by white blood cells, particularly monocytes and macrophages. |
| The pyrogen test is a safety test for the detection of contaminants in medical products. |
| Sheaths that contact brain tissue must be pyrogen free. |
| He is responsible for all pyrogen and bacterial endotoxins testing issues. |
