| A gift under which the beneficiaries are defined by reference to a purely personal relationship to a named propositus cannot on principle be a valid charitable gift. |
| Key relatives included siblings, parents, offspring, grandparents, first uncles and aunts, and the propositus. |
| The propositus was an elderly man who passed on the disorder to three of his four children and 9 of 14 grandchildren. |
| Mutations were checked against parental DNA for each propositus. |
| This variant was named Hb Gorwihl after the city where the propositus lived. |
| Therefore, we stratified the single group analyses, including only the propositus of each family. |
