| Several medications have been known to induce scleroderma-like clinical conditions including bleomycin, docetaxel, and penicillamine. |
| Adverse effects of penicillamine include rash, leukopenia, thrombocytopenia, hematuria, proteinuria, eosinophilia, elevated liver enzyme levels and nephrotoxicity. |
| A OTHER disease-modifying drugs, such as the gold injections, are penicillamine, sulphasalazine and chloroquine. |
| Chelating agents, such as penicillamine and gold compounds, such as auranofin are used to decrease inflammation and to slow the destruction of joint tissue. |
| Idiosyncratic renal damage may be secondary to NSAIDs, penicillins, gold and penicillamine. |
