| Diseases of the endocrine system can result from the oversecretion or undersecretion of hormones or from the inability of target organs or tissues to respond to hormones effectively. |
| Gigantism or acromegaly — in which a tumor on the pituitary gland causes an oversecretion of growth hormone — may be the cause of his condition. |
| In susceptible individuals, there is oversecretion of sebum. |
| In this way the tubes become choked and obstructed with the oversecretion or by swelling. |
| Excessive pigmentation can be caused by oversecretion of adrenocorticotrophic hormones and an associated melanocyte-stimulating hormone from the pituitary gland. |
| Black used a similar approach to develop a drug treatment for stomach and duodenal ulcers, which are largely caused by the stomach's oversecretion of gastric acids. |
