| Using them without consulting a doctor can result in hyperpigmentation or ochronosis, a bluish black discolouration of the skin. |
| O'Brien WM, La Du BN, Bunim JJ Biochemical, pathologic and clinical aspects of alkaptonuria, ochronosis and ochronotic arthropathy. |
| Other important consequences of alcaptonuric ochronosis are aortic valve stenosis and urinary tract involvement. |
| Prolonged use of this ingredient thickens collagen fibers, resulting in ochronosis. |
| As a result, a black pigment, called ochronosis, forms and binds to bone, cartilage and skin. |
| There are dermatological problems such as striae atrophica, colloid milium ochronosis, scabies, cutaneous atrophy and pitch black pigmentation. |
