| Isolation of different cell types by laser capture microdissection is being used to identify distinct signatures for early stage disease, metastatic lesions, tumour stroma and tumour vasculature. |
| It is a very powerful tool to explore tissues to discover and to validate new therapeutic markers identified by molecular methods such as DNA chips, mass spec, Q-PCR, laser microdissection. |
| We are also using laser capture microdissection and label free LC-S technologies to profile protein expression in blood capillaries isolated from normal and malignant breast tissues. |
| As a first, ALPHELYS will introduce the new ARCTURUS solutions for laser microdissection with the latest generation of Instruments VERITAS and the new Paradise Kit for RNA extraction from fixed tissues. |
| Some reagents are proposed to inhibit RNAses but they usually strongly alter morphology which severely makes tissue structure and cell recognition difficult while it is a crucial argument for laser microdissection. |
| Adhering to the PSA® tape, the tissue section stays perfectly in place until mounting for an ideal contact between Arcturus Pixcell® capsure and the section for an improvement microdissection accuracy. |
