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What does metastasized mean?

Looking for the meaning or definition of the word metastasized? Here's what it means.

Verb
  1. simple past tense and past participle of metastasize
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If the tumor has already metastasized before local therapy is administered, cure is impossible.
It had already metastasized to his spinal column and his bony pelvis, femurs, skull, and tibia.
In 70 percent of these cases, the cancer will have metastasized, or spread to other areas of the body.
Mrs. J., age 72, has breast cancer, which has metastasized to the bone and brain.
She has just learned she has advanced ovarian cancer, which has metastasized to the stomach.
At one point there was concern as to whether or not cancer cells had metastasized to my bones.

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