| In addition to supporting platform technologies, the TB Alliance is developing nitroimidazopyrans, quinolones, macrolides and other classes of antibiotics. |
| The most common classes of antibiotics used in medicine include penicillin, cephalosporins, aminoglycosides, macrolides, quinolones and tetracyclines. |
| Failures occurred most commonly with nitrofurans, sulfonamides, fluoroquinolones, cephalosporins, and macrolides. |
| Antibiotic categories to consider include penicillins, cephalosporins, and macrolides. |
| Solithromycin has greater in vitro activity compared to current macrolides, including macrolide-resistant strains. |
| Oral antibiotic therapy with macrolides and cephalosporines for presumed pneumonia was started, with a favorable response after 5 days of therapy. |
