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What does macrocyclic mean?

Looking for the meaning or definition of the word macrocyclic? Here's what it means.

Adjective
  1. (chemistry) having a closed ring of more than about twelve atoms
  2. (chemistry) of, or relating to a macrocycle
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Examples
It also validates our chemistry technology in the successful develop-ment of a small molecule macrocyclic compound as a clinical candidate.
Use of macrocyclic ligands for diagnosing neurodegenerative diseases, including Alzheimer.
The polar head is a macrocyclic lactone ring containing nine amino acid residues, three of which have positive charges, whereas one has negative charge.
A Technetium complex of a crown thioether having 3 to 6 donor sulphur atoms joined into a macrocyclic ring by C2 or C3 groups.
Collectively, they are called tetraamido macrocyclic ligands or TAML for short.
Epothilones, macrocyclic lactones from culture filtrates of the myxobacterium Sorangium cellulosum, are known as taxol-like microtubular drugs in human medicine.

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