One of the 6 major subgroups of flavenoids is the subgroup of Flavone including Flavon, Apigenin and Luteolin, which all three exist in chamomile. |
The investigators found two major peaks in the chromatograms of the hull extracts, which they identified as luteolin and the flavanone fustin. |
For reference rutin, quercetin, galangin and luteolin standards were used. |
Chief among these is cynaropicrin, along with luteolin, cynaroside, and chlorogenic acid. |
Upon acid hydrolysis compound II gave luteolin in the lipophilic layer and glucose in the hydrophilic layer. |
The finding that the natural phytomolecule luteolin can act as a SphK2 inhibitor may have implications in this field, and in developing this class of inhibitors. |