By binding intramolecularly to the receptor, the tethered ligand causes transmembrane signaling. |
By adding and subtracting methyl groups, the two enzymes can adjust receptor sensitivity to mitigate the effect of ligand binding. |
His study elucidated the effects of ligand structure and electronics on catalytic activity. |
The Netropsin ligand consists of a guanidinium, two pyrrole, and a propylamidinium part. |
Their implications for catalytic function and ligand interaction are discussed. |
Indeed, ion channels, whether gated by ligand, voltage, or force, all possess specialized molecular sensors for detection of their stimuli. |