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What is a ligand?

What is a ligand? Here are some definitions.

Noun
  1. (chemistry) An ion, molecule, or functional group that binds to another chemical entity to form a larger complex.
  2. (typography) A letter that orthography requires be ligated with one or more other letters.
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Examples
By binding intramolecularly to the receptor, the tethered ligand causes transmembrane signaling.
By adding and subtracting methyl groups, the two enzymes can adjust receptor sensitivity to mitigate the effect of ligand binding.
His study elucidated the effects of ligand structure and electronics on catalytic activity.
The Netropsin ligand consists of a guanidinium, two pyrrole, and a propylamidinium part.
Their implications for catalytic function and ligand interaction are discussed.
Indeed, ion channels, whether gated by ligand, voltage, or force, all possess specialized molecular sensors for detection of their stimuli.

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