| This surplus having to be eliminated by the classical process of the keratinization. |
| Neoplastic cells may be oval, polyhedral, spindle-shaped, or giant, although in an undifferentiated carcinoma they present as small cells without keratinization. |
| Additionally, skeletal hyperostosis was noted in six of eight patients in a prospective study of disorders of keratinization. |
| It controls the process of keratinization, humidifies and regenerates the skin, while making it flexible and smooth. |
| Prolonged lack of vitamin A leads to deterioration of the eye tissue through progressive keratinization of the cornea, a condition known as xerophthalmia. |
| Vitamin A is important for functional integrity of the skin and is known to affect the keratinization process. |
