The expression of integrins on the cell surface facilitates adhesion. |
The activated PS2-containing integrins are clustered in basal plaques on each cell, but the PS1-containing heterodimers are not. |
Integrins are an ancient group of animal adhesion receptors that attach cells to the extracellular matrix. |
This process is coordinately regulated by the spatial and temporal expression of integrins across the cell surface. |
The elucidation of the fly genome makes it relatively straightforward to generate and study mutations in proteins previously associated with integrins from other systems. |
We measured the effect of cytochalasin D mobilization of integrins on adhesion of a leukocyte cell line to both cultured endothelium and purified ligand substrates. |